{"id":101647,"date":"2018-03-11T10:23:33","date_gmt":"2018-03-11T10:23:33","guid":{"rendered":"https:\/\/www.deberes.net\/tesis\/sin-categoria\/estudios-fitoqua%c2%admicos-y-de-la-actividad-antioxidante-anticolinesterasica-y-antifungica-de-jungia-paniculata-y-chuquiraga-spinosa-asteraceae\/"},"modified":"2018-03-11T10:23:33","modified_gmt":"2018-03-11T10:23:33","slug":"estudios-fitoqua%c2%admicos-y-de-la-actividad-antioxidante-anticolinesterasica-y-antifungica-de-jungia-paniculata-y-chuquiraga-spinosa-asteraceae","status":"publish","type":"post","link":"https:\/\/www.deberes.net\/tesis\/farmacognosia\/estudios-fitoqua%c2%admicos-y-de-la-actividad-antioxidante-anticolinesterasica-y-antifungica-de-jungia-paniculata-y-chuquiraga-spinosa-asteraceae\/","title":{"rendered":"Estudios fitoqu\u00edmicos y de la actividad antioxidante, anticolinester\u00e1sica y antif\u00fangica de jungia paniculata y chuquiraga spinosa (asteraceae)"},"content":{"rendered":"

Tesis doctoral de Raquel Casado Arboni\u00e9s <\/strong><\/h2>\n

Uno de los objetivos de este trabajo fue la b\u00fasqueda de actividad antioxidante, anticolinester\u00e1sica y antif\u00fangica en los extractos de jungia paniculata dc a. Gray (asteraceae) y chuquiraga spinosa (r. Et p.) D. Don (asteraceae), dos plantas muy empleadas en la medicina tradicional de per\u00fa. se prepararon extractos polares (metan\u00f3licos, etan\u00f3licos 50% y acuosos) a partir de las partes a\u00e9reas secas y tambi\u00e9n de acetato de etilo y diclorometano en el caso de j. Paniculata. los extractos polares de las dos especies mostraron actividad antirradicalaria frente a tres radicales libres (dpph˙, abts˙+ y radical super\u00f3xido). no se detect\u00f3 actividad inhibitoria de la enzima acetilcolinesterasa en ninguno de los extractos. los extractos acuoso e hidroalcoh\u00f3lico de c. Spinosa presentaron actividad antif\u00fangica frente a candida albicans (dosis m\u00ednima inhibitoria de 2,50 \u00c2\u00b5g y 6,25 \u00c2\u00b5g, respectivamente). los extractos de acetato de etilo y diclorometano de j. Paniculata fueron los m\u00e1s activos frente a rhizopus stolonifer, alcanzando valores en torno al 50% de inhibici\u00f3n. Ninguno de los extractos de chuquiraga spinosa super\u00f3 un porcentaje de inhibici\u00f3n de 20%. otro de los objetivos de este trabajo de investigaci\u00f3n fue ampliar el conocimiento acerca de la composici\u00f3n qu\u00edmica de ambas especies. en jungia paniculata se identificaron luteol\u00edn-7-o-ramnosil-glucuronosil-glucur\u00f3nido y apigen\u00edn-7-o-ramnosil-glucuronosil-glucur\u00f3nido y tres \u00e1cidos fen\u00f3licos (\u00e1cido clorog\u00e9nico, \u00e1cido cafeico y \u00e1cido dicafeoilqu\u00ednico). se aislaron e identificaron tres flavonoides acilados en los extractos de chuquiraga spinosa: quercet\u00edn-3-o-β-d-(6\u00c2\u00bf-feruloil)-gluc\u00f3sido, kaemferol-3-o-β-d-(6\u00c2\u00bf-feruloil)-gluc\u00f3sido e isoramnet\u00edn-3-o-β-d-(6\u00c2\u00bf-feruloil)-gluc\u00f3sido, adem\u00e1s de dos derivados de \u00e1cido cafeico. Ninguno de estos compuestos hab\u00eda sido descrito previamente en estas especies. se cuantific\u00f3 la actividad antioxidante frente al dpph˙ de los flavonoides y derivados de \u00e1cidos fen\u00f3licos identificados hasta el momento en estas plantas estableciendo interesantes relaciones estructura-actividad.<\/p>\n

 <\/p>\n

Datos acad\u00e9micos de la tesis doctoral \u00abEstudios fitoqu\u00edmicos y de la actividad antioxidante, anticolinester\u00e1sica y antif\u00fangica de jungia paniculata y chuquiraga spinosa (asteraceae)<\/strong>\u00ab<\/h3>\n
    \n
  • T\u00edtulo de la tesis:<\/strong>\u00a0 Estudios fitoqu\u00edmicos y de la actividad antioxidante, anticolinester\u00e1sica y antif\u00fangica de jungia paniculata y chuquiraga spinosa (asteraceae) <\/li>\n
  • Autor:<\/strong>\u00a0 Raquel Casado Arboni\u00e9s <\/li>\n
  • Universidad:<\/strong>\u00a0 Navarra<\/li>\n
  • Fecha de lectura de la tesis:<\/strong>\u00a0 15\/06\/2010<\/li>\n<\/ul>\n

     <\/p>\n

    Direcci\u00f3n y tribunal<\/h3>\n
      \n
    • Director de la tesis<\/strong>\n
        \n
      • Mar\u00eda Isabel Calvo Mart\u00ednez<\/li>\n<\/ul>\n<\/li>\n
      • Tribunal<\/strong>\n
          \n
        • Presidente del tribunal: Mar\u00eda teresa Ortega hernandez agero <\/li>\n
        • M\u00aa pilar Almajano pablos (vocal)<\/li>\n
        • nuria Vilalta clemente (vocal)<\/li>\n
        • diana Mar\u00eda Ansorena artieda (vocal)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n

           <\/p>\n","protected":false},"excerpt":{"rendered":"

          Tesis doctoral de Raquel Casado Arboni\u00e9s Uno de los objetivos de este trabajo fue la b\u00fasqueda de actividad antioxidante, anticolinester\u00e1sica […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[489,17749],"tags":[106387,124362,189525,206510,206511,206509],"class_list":["post-101647","post","type-post","status-publish","format-standard","hentry","category-farmacognosia","category-navarra","tag-diana-maria-ansorena-artieda","tag-maria-isabel-calvo-Martinez","tag-maria-teresa-ortega-hernandez-agero","tag-ma-pilar-almajano-pablos","tag-nuria-vilalta-clemente","tag-raquel-casado-arbonies"],"_links":{"self":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/101647","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/comments?post=101647"}],"version-history":[{"count":0,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/101647\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/media?parent=101647"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/categories?post=101647"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/tags?post=101647"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}