{"id":105536,"date":"2010-10-12T00:00:00","date_gmt":"2010-10-12T00:00:00","guid":{"rendered":"https:\/\/www.deberes.net\/tesis\/sin-categoria\/evaluacion-mediante-ecografa%c2%ada-doppler-color-del-efecto-de-la-combinacion-fija-bimatoprost-03-mg-ml-timolol-5-mg-ml-en-el-flujo-sangua%c2%adneo-ocular-en-pacientes-con-hipertension-ocular\/"},"modified":"2010-10-12T00:00:00","modified_gmt":"2010-10-12T00:00:00","slug":"evaluacion-mediante-ecografa%c2%ada-doppler-color-del-efecto-de-la-combinacion-fija-bimatoprost-03-mg-ml-timolol-5-mg-ml-en-el-flujo-sangua%c2%adneo-ocular-en-pacientes-con-hipertension-ocular","status":"publish","type":"post","link":"https:\/\/www.deberes.net\/tesis\/oftalmologia\/evaluacion-mediante-ecografa%c2%ada-doppler-color-del-efecto-de-la-combinacion-fija-bimatoprost-03-mg-ml-timolol-5-mg-ml-en-el-flujo-sangua%c2%adneo-ocular-en-pacientes-con-hipertension-ocular\/","title":{"rendered":"Evaluaci\u00f3n mediante ecograf\u00edadoppler color del efecto de la combinaci\u00f3n fija bimatoprost (0,3 mg\/ml)\/timolol (5 mg\/ml) en el flujo sangu\u00edneo ocular en pacientes con hipertensi\u00f3n ocular"},"content":{"rendered":"

Tesis doctoral de Jorge Luis Garc\u00eda P\u00e9rez <\/strong><\/h2>\n

Objetivo: el prop\u00f3sito de esta tesis doctoral fue analizar el efecto de la combinaci\u00f3n fija bimatoprost (0,3 mg\/ml)\/timolol (5 mg\/ml) (cfbt) sobre la hemodin\u00e1mica retrobulbar de pacientes hipertensos oculares pacientes y m\u00e9todos: se trat\u00f3 de un estudio unic\u00e9ntrico, prospectivo, doble ciego, aleatorizado y controlado con placebo. Se incluyeron 30 ojos de 30 pacientes hipertensos oculares y fueron aleatoriamente asignados a uno de los dos grupos de tratamiento (grupo de la cfbt, n=15; grupo placebo n=15). La realizaci\u00f3n de una ecograf\u00eda doppler color para la obtenci\u00f3n de par\u00e1metros hemodin\u00e1micos en la arteria oft\u00e1lmica y arteria central de la retina (acr), as\u00ed como una exploraci\u00f3n oftalmol\u00f3gica completa fueron llevados a cabo basalmente y a las 12 semanas de tratamiento. Tambi\u00e9n se registraron la tensi\u00f3n arterial y la frecuencia card\u00edaca. resultados: la cfbt disminuy\u00f3 la presi\u00f3n intraocular (pio) 7,3 mmhg (p<0,0001) y aument\u00f3 de forma significativa la velocidad diast\u00f3lica final (vdf) en la acr 1,3 cm\/s (p=0,01). No se encontr\u00f3 ning\u00fan otro efecto de la cfbt sobre la hemodin\u00e1mica retrobulbar ni sobre los par\u00e1metros oftalmol\u00f3gicos y sist\u00e9micos registrados. Se encontr\u00f3 una relaci\u00f3n estad\u00edsticamente significativa entre la disminuci\u00f3n de la pio y el aumento de la vdf (r=-0,627, p=0,013) y el descenso del ir (r=0,481, p=0,035) en la acr a las 12 semanas de tratamiento. conclusiones: la cbft redujo significativamente la pio en pacientes hipertensos oculares. Sin embargo, el \u00fanico cambio observado en la hemodin\u00e1mica retrobulbar fue un incremento de la vdf en la acr, probablemente relacionado con la importante reducci\u00f3n de pio conseguida.\n\n\n\n \n\n\n

Datos acad\u00e9micos de la tesis doctoral \u00abEvaluaci\u00f3n mediante ecograf\u00edadoppler color del efecto de la combinaci\u00f3n fija bimatoprost (0,3 mg\/ml)\/timolol (5 mg\/ml) en el flujo sangu\u00edneo ocular en pacientes con hipertensi\u00f3n ocular<\/strong>\u00ab<\/h3>\n
    \n
  • T\u00edtulo de la tesis:<\/strong>\u00a0 Evaluaci\u00f3n mediante ecograf\u00edadoppler color del efecto de la combinaci\u00f3n fija bimatoprost (0,3 mg\/ml)\/timolol (5 mg\/ml) en el flujo sangu\u00edneo ocular en pacientes con hipertensi\u00f3n ocular <\/li>\n
  • Autor:<\/strong>\u00a0 Jorge Luis Garc\u00eda P\u00e9rez <\/li>\n
  • Universidad:<\/strong>\u00a0 Alcal\u00e1<\/li>\n
  • Fecha de lectura de la tesis:<\/strong>\u00a0 10\/12\/2010<\/li>\n<\/ul>\n

     <\/p>\n

    Direcci\u00f3n y tribunal<\/h3>\n
      \n
    • Director de la tesis<\/strong>\n
        \n
      • Gema Rebolleda Fernandez<\/li>\n<\/ul>\n<\/li>\n
      • Tribunal<\/strong>\n
          \n
        • Presidente del tribunal: Juan Murube del castillo <\/li>\n
        • Jos\u00e9 Manuel Larrosa poves (vocal)<\/li>\n
        • Rafael Morcillo la\u00edz (vocal)<\/li>\n
        • Juli\u00e1n Garcia feijoo (vocal)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n

           <\/p>\n","protected":false},"excerpt":{"rendered":"

          Tesis doctoral de Jorge Luis Garc\u00eda P\u00e9rez Objetivo: el prop\u00f3sito de esta tesis doctoral fue analizar el efecto de la […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[17426,988],"tags":[202337,212804,131523,15480,65404,212805],"class_list":["post-105536","post","type-post","status-publish","format-standard","hentry","category-alcala","category-oftalmologia","tag-gema-rebolleda-fernandez","tag-jorge-luis-garcia-perez","tag-jose-manuel-larrosa-poves","tag-juan-murube-del-castillo","tag-julian-garcia-feijoo","tag-rafael-morcillo-laiz"],"_links":{"self":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/105536","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/comments?post=105536"}],"version-history":[{"count":0,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/105536\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/media?parent=105536"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/categories?post=105536"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/tags?post=105536"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}