{"id":107405,"date":"2018-03-11T10:31:45","date_gmt":"2018-03-11T10:31:45","guid":{"rendered":"https:\/\/www.deberes.net\/tesis\/sin-categoria\/expresion-de-mucinas-y-moleculas-relacionadas-en-carcinomas-mucoepidermoides-de-glandulas-salivales-implicaciones-diagnosticas-y-pronosticas\/"},"modified":"2018-03-11T10:31:45","modified_gmt":"2018-03-11T10:31:45","slug":"expresion-de-mucinas-y-moleculas-relacionadas-en-carcinomas-mucoepidermoides-de-glandulas-salivales-implicaciones-diagnosticas-y-pronosticas","status":"publish","type":"post","link":"https:\/\/www.deberes.net\/tesis\/histopatologia\/expresion-de-mucinas-y-moleculas-relacionadas-en-carcinomas-mucoepidermoides-de-glandulas-salivales-implicaciones-diagnosticas-y-pronosticas\/","title":{"rendered":"Expresi\u00f3n de mucinas y mol\u00e9culas relacionadas en carcinomas mucoepidermoides de gl\u00e1ndulas salivales: implicaciones diagn\u00f3sticas y pron\u00f3sticas."},"content":{"rendered":"<h2>Tesis doctoral de <strong> Blanca Noem\u00ed Luj\u00e1n <\/strong><\/h2>\n<p>El carcinoma mucoepidermoide, es el tumor maligno m\u00e1s frecuente de gl\u00e1ndulas salivales (gs). Tanto su expresi\u00f3n de mucinas, muc1 y muc4, como el n\u00famero de copias del gen egfr (receptor del factor de crecimiento epid\u00e9rmico) y la expresi\u00f3n de erk1\/2, se correlacionan con el grado histol\u00f3gico y con el pron\u00f3stico de estos tumores. Los carcinomas mucoepidermoides (cmes) de alto grado, de gs, tienen una alta expresi\u00f3n de muc1 y baja de muc4, as\u00ed como, un aumento del n\u00famero de copias del gen egfr y alta expresi\u00f3n de erk1\/2, las que se correlacionan con la progresi\u00f3n de la enfermedad.  por lo tanto, la alta expresi\u00f3n de muc1 y la activaci\u00f3n de la v\u00eda efectora egfr\/erk de los cmes de alto grado, de gs, podr\u00edan seleccionar pacientes como candidatos a tratamientos dirigidos contra estas dianas terap\u00e9uticas.<\/p>\n<p>&nbsp;<\/p>\n<h3>Datos acad\u00e9micos de la tesis doctoral \u00ab<strong>Expresi\u00f3n de mucinas y mol\u00e9culas relacionadas en carcinomas mucoepidermoides de gl\u00e1ndulas salivales: implicaciones diagn\u00f3sticas y pron\u00f3sticas.<\/strong>\u00ab<\/h3>\n<ul>\n<li><strong>T\u00edtulo de la tesis:<\/strong>\u00a0 Expresi\u00f3n de mucinas y mol\u00e9culas relacionadas en carcinomas mucoepidermoides de gl\u00e1ndulas salivales: implicaciones diagn\u00f3sticas y pron\u00f3sticas. <\/li>\n<li><strong>Autor:<\/strong>\u00a0 Blanca Noem\u00ed Luj\u00e1n <\/li>\n<li><strong>Universidad:<\/strong>\u00a0 Barcelona<\/li>\n<li><strong>Fecha de lectura de la tesis:<\/strong>\u00a0 16\/03\/2011<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h3>Direcci\u00f3n y tribunal<\/h3>\n<ul>\n<li><strong>Director de la tesis<\/strong>\n<ul>\n<li>Ll\u00facia Al\u00f3s Hern\u00e1ndez<\/li>\n<\/ul>\n<\/li>\n<li><strong>Tribunal<\/strong>\n<ul>\n<li>Presidente del tribunal: josep antoni Bomb\u00ed latorre <\/li>\n<li>pere Huguet redecilla (vocal)<\/li>\n<li>  (vocal)<\/li>\n<li>  (vocal)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tesis doctoral de Blanca Noem\u00ed Luj\u00e1n El carcinoma mucoepidermoide, es el tumor maligno m\u00e1s frecuente de gl\u00e1ndulas salivales (gs). Tanto [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[951,8901,52,347],"tags":[215739,14013,75670,128648],"class_list":["post-107405","post","type-post","status-publish","format-standard","hentry","category-barcelona","category-carcinogenesis","category-histopatologia","category-oncologia-clinica","tag-blanca-noemi-lujan","tag-josep-antoni-bombi-latorre","tag-llucia-alos-hernandez","tag-pere-huguet-redecilla"],"_links":{"self":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/107405","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/comments?post=107405"}],"version-history":[{"count":0,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/107405\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/media?parent=107405"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/categories?post=107405"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/tags?post=107405"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}