{"id":109878,"date":"2011-05-07T00:00:00","date_gmt":"2011-05-07T00:00:00","guid":{"rendered":"https:\/\/www.deberes.net\/tesis\/sin-categoria\/feature-selection-methods-for-the-generation-of-signatures-to-study-the-non-alcoholic-fatty-liver-disease\/"},"modified":"2011-05-07T00:00:00","modified_gmt":"2011-05-07T00:00:00","slug":"feature-selection-methods-for-the-generation-of-signatures-to-study-the-non-alcoholic-fatty-liver-disease","status":"publish","type":"post","link":"https:\/\/www.deberes.net\/tesis\/biologia-celular\/feature-selection-methods-for-the-generation-of-signatures-to-study-the-non-alcoholic-fatty-liver-disease\/","title":{"rendered":"Feature selection methods for the generation of signatures to study the non alcoholic fatty liver disease"},"content":{"rendered":"<h2>Tesis doctoral de <strong> Mar\u00eda  Iciar Frades Alzueta <\/strong><\/h2>\n<p>This thesis focuses in the analysis of microarray expression data, proteomics and machine learning  centering  on  the  development  of  feature  subset  selection  algorithms  for  biomarker identification  and  genomic  signature  generation  of  genes  and  pathways  to  study  the  non alcoholic  fatty liver  disease. molecular  signatures  from microarrays  have  been  used  to  determine  the non alcoholic  fatty liver  disease  outcomes,  prognostic,  mechanisms,  targets,  and  treatment  strategies  by understanding  the  processes  responsible  for  the  differences  between  states.  To  generate  the signatures  in  this  study we  have  adapted  and  implemented  a  representative  set  of  31  feature selection  methods  making  use  of  adequate  evaluation  criteria  and  stable  and  robust  feature selection models. Many of the feature selection methods are adapted for microarray analysis so they generate signatures classifying disease based not only on the activity of individual genes but also on the activity of signaling pathways. One of the goals of these modeling studies is to build classifiers to predict the outcome of future observations. We work towards designing some diagnostic and prognostic models for the non alcoholic fatty liver disease.  these  methods  are  also  used  to  predict  posttranslational  phosphorylation  modifications  in ms\/ms spectra.<\/p>\n<p>&nbsp;<\/p>\n<h3>Datos acad\u00e9micos de la tesis doctoral \u00ab<strong>Feature selection methods for the generation of signatures to study the non alcoholic fatty liver disease<\/strong>\u00ab<\/h3>\n<ul>\n<li><strong>T\u00edtulo de la tesis:<\/strong>\u00a0 Feature selection methods for the generation of signatures to study the non alcoholic fatty liver disease <\/li>\n<li><strong>Autor:<\/strong>\u00a0 Mar\u00eda  Iciar Frades Alzueta <\/li>\n<li><strong>Universidad:<\/strong>\u00a0 Pa\u00eds vasco\/euskal herriko unibertsitatea<\/li>\n<li><strong>Fecha de lectura de la tesis:<\/strong>\u00a0 05\/07\/2011<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h3>Direcci\u00f3n y tribunal<\/h3>\n<ul>\n<li><strong>Director de la tesis<\/strong>\n<ul>\n<li>M\u00aa Luz Martinez Chantar<\/li>\n<\/ul>\n<\/li>\n<li><strong>Tribunal<\/strong>\n<ul>\n<li>Presidente del tribunal: alfonso Valencia herrera <\/li>\n<li>Jes\u00fas m. Arizmendi bastarrika (vocal)<\/li>\n<li>francesc Giralt prat (vocal)<\/li>\n<li>Alberto Pascual montano (vocal)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tesis doctoral de Mar\u00eda Iciar Frades Alzueta This thesis focuses in the analysis of microarray expression data, proteomics and machine [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[849,12909],"tags":[61440,37139,30329,209203,219593,87917],"class_list":["post-109878","post","type-post","status-publish","format-standard","hentry","category-biologia-celular","category-pais-vasco-euskal-herriko-unibertsitatea","tag-alberto-pascual-montano","tag-alfonso-valencia-herrera","tag-francesc-giralt-prat","tag-jesus-m-arizmendi-bastarrika","tag-maria-iciar-frades-alzueta","tag-ma-luz-Martinez-chantar"],"_links":{"self":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/109878","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/comments?post=109878"}],"version-history":[{"count":0,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/109878\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/media?parent=109878"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/categories?post=109878"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/tags?post=109878"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}