{"id":110536,"date":"2018-03-11T10:36:35","date_gmt":"2018-03-11T10:36:35","guid":{"rendered":"https:\/\/www.deberes.net\/tesis\/sin-categoria\/cambios-en-los-niveles-de-apoptosis-de-neutrofilos-en-pacientes-con-shock-septico-diferencias-entre-supervivientes-y-no-supervivientes\/"},"modified":"2018-03-11T10:36:35","modified_gmt":"2018-03-11T10:36:35","slug":"cambios-en-los-niveles-de-apoptosis-de-neutrofilos-en-pacientes-con-shock-septico-diferencias-entre-supervivientes-y-no-supervivientes","status":"publish","type":"post","link":"https:\/\/www.deberes.net\/tesis\/ciencias-medicas\/cambios-en-los-niveles-de-apoptosis-de-neutrofilos-en-pacientes-con-shock-septico-diferencias-entre-supervivientes-y-no-supervivientes\/","title":{"rendered":"Cambios en los niveles de apoptosis de neutr\u00f3filos en pacientes con shock s\u00e9ptico. diferencias entre supervivientes y no supervivientes"},"content":{"rendered":"

Tesis doctoral de Esther G\u00f3mez S\u00e1nchez <\/strong><\/h2>\n

Objetivo: el mecanismo normal de eliminaci\u00f3n de neutr\u00f3filos es la apoptosis o muerte celular programada. El prop\u00f3sito de este estudio es caracterizar la evoluci\u00f3n de la apoptosis de neutr\u00f3filos en pacientes con shock s\u00e9ptico. El objetivo principal es evaluar si los niveles de apoptosis de neutr\u00f3filos se han incrementado y son comparables a los de los sujetos sanos a los 1, 5 y 12 d\u00edas de la evoluci\u00f3n de la sepsis. m\u00e9todo: estudio abierto, prospectivo, no aleatorizado y multic\u00e9ntrico en el que se evaluar\u00e1 la apoptosis de neutr\u00f3filos en 80 pacientes con shock s\u00e9ptico en comparaci\u00f3n con 25 voluntarios sanos. resultados: en los pacientes s\u00e9pticos la media de apoptosis (\u00c2\u00b1 error standard de la media, esm) fue menor que en voluntarios sanos el primer d\u00eda y a lo largo de la evoluci\u00f3n de la enfermedad. Sanos (37,6% \u00c2\u00b1 12,8%); s\u00e9pticos primer d\u00eda (14,8% \u00c2\u00b1 13,4%; p < .001); s\u00e9pticos quinto d\u00eda (13,4% \u00c2\u00b1 8,4%; p < .001); s\u00e9pticos duod\u00e9cimo d\u00eda (15,4% \u00c2\u00b1 12,8%; p < .001). No hubo diferencias significativas en apoptosis entre no supervivientes (ns) supervivientes (s) a lo largo de los 12 d\u00edas de evoluci\u00f3n: primer d\u00eda p= .63; quinto d\u00eda p= .74; duod\u00e9cimo d\u00eda p= .54). conclusiones: durante la sepsis grave\/shock s\u00e9ptico se produce una disminuci\u00f3n de los niveles de apoptosis. Esta alteraci\u00f3n no se recupera a lo largo de 12 d\u00edas de evoluci\u00f3n de la enfermedad.\n\n\n\n \n\n\n

Datos acad\u00e9micos de la tesis doctoral \u00abCambios en los niveles de apoptosis de neutr\u00f3filos en pacientes con shock s\u00e9ptico. diferencias entre supervivientes y no supervivientes<\/strong>\u00ab<\/h3>\n
    \n
  • T\u00edtulo de la tesis:<\/strong>\u00a0 Cambios en los niveles de apoptosis de neutr\u00f3filos en pacientes con shock s\u00e9ptico. diferencias entre supervivientes y no supervivientes <\/li>\n
  • Autor:<\/strong>\u00a0 Esther G\u00f3mez S\u00e1nchez <\/li>\n
  • Universidad:<\/strong>\u00a0 Valladolid<\/li>\n
  • Fecha de lectura de la tesis:<\/strong>\u00a0 22\/07\/2011<\/li>\n<\/ul>\n

     <\/p>\n

    Direcci\u00f3n y tribunal<\/h3>\n
      \n
    • Director de la tesis<\/strong>\n
        \n
      • Jos\u00e9 Ignacio G\u00f3mez Herreras<\/li>\n<\/ul>\n<\/li>\n
      • Tribunal<\/strong>\n
          \n
        • Presidente del tribunal: Francisco javier Casta\u00f1eda casado <\/li>\n
        • pablo Monedero rodr\u00edguez (vocal)<\/li>\n
        • Fernando Gilsanz rodr\u00edguez (vocal)<\/li>\n
        • clemente Muriel villoria (vocal)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n

           <\/p>\n","protected":false},"excerpt":{"rendered":"

          Tesis doctoral de Esther G\u00f3mez S\u00e1nchez Objetivo: el mecanismo normal de eliminaci\u00f3n de neutr\u00f3filos es la apoptosis o muerte celular […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[9,12451],"tags":[9871,220617,30129,9211,185829,71033],"class_list":["post-110536","post","type-post","status-publish","format-standard","hentry","category-ciencias-medicas","category-valladolid","tag-clemente-muriel-villoria","tag-esther-gomez-sanchez","tag-fernando-gilsanz-rodriguez","tag-francisco-javier-castaneda-casado","tag-jose-ignacio-gomez-herreras","tag-pablo-monedero-rodriguez"],"_links":{"self":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/110536","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/comments?post=110536"}],"version-history":[{"count":0,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/110536\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/media?parent=110536"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/categories?post=110536"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/tags?post=110536"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}