{"id":114222,"date":"2018-03-11T10:42:09","date_gmt":"2018-03-11T10:42:09","guid":{"rendered":"https:\/\/www.deberes.net\/tesis\/sin-categoria\/oxido-na%c2%adtrico-exhalado-y-asma-metodologa%c2%ada-interpretacion-de-los-resultados-y-aplicaciones-en-ninos\/"},"modified":"2018-03-11T10:42:09","modified_gmt":"2018-03-11T10:42:09","slug":"oxido-na%c2%adtrico-exhalado-y-asma-metodologa%c2%ada-interpretacion-de-los-resultados-y-aplicaciones-en-ninos","status":"publish","type":"post","link":"https:\/\/www.deberes.net\/tesis\/neurociencias\/oxido-na%c2%adtrico-exhalado-y-asma-metodologa%c2%ada-interpretacion-de-los-resultados-y-aplicaciones-en-ninos\/","title":{"rendered":"\u00f3xido n\u00edtrico exhalado y asma: metodolog\u00eda, interpretaci\u00f3n de los resultados y aplicaciones en ni\u00f1os"},"content":{"rendered":"

Tesis doctoral de Paula Corcuera Elosegui <\/strong><\/h2>\n

El \u00f3xido n\u00edtrico exhalado (eno) es un marcador indirecto de la inflamaci\u00f3n asm\u00e1tica y se recomienda su determinaci\u00f3n en ni\u00f1os para el diagn\u00f3stico de la enfermedad, monitorizaci\u00f3n del tratamiento y control evolutivo.Este proyecto de investigaci\u00f3n, prospectivo, observacional y transversal se dirige a profundizar en (1) aspectos t\u00e9cnicos parciales o desconocidos, como son la determinaci\u00f3n de la fracci\u00f3n exhalada de \u00f3xido n\u00edtrico con medidores port\u00e1tiles, la reducci\u00f3n del tiempo espiratorio, con respiraci\u00f3n \u00fanica o m\u00faltiple; (2) la obtenci\u00f3n de las variables de normalidad derivadas del \u00f3xido n\u00edtrico alveolar; (3) la relaci\u00f3n entre las medidas de control del asma (funci\u00f3n pulmonar, cuestionarios de calidad de vida, \u00edndice predictivo de asma) y el \u00f3xido n\u00edtrico exhalado; y (4) si el patr\u00f3n de \u00f3xido n\u00edtrico alveolar en el asma controlado y no controlado tiene expresi\u00f3n fenot\u00edpica.Estos objetivos se han llevado a cabo a trav\u00e9s de una l\u00ednea de investigaci\u00f3n durante los 8 \u00faltimos a\u00f1os, en el laboratorio de funci\u00f3n pulmonar de la secci\u00f3n de neumolog\u00eda pedi\u00e1trica, en el hospital universitario donostia, campus de gipuzkoa, upv\/ehu, determinando el eno proximal mediante analizador de quimioluminiscencia estacionario, analizador electroqu\u00edmico, a respiraci\u00f3n \u00fanica o m\u00faltiples, con tiempo espiratorios de 6 y 10 segundos, con flujos de 50 ml\/s y con restrictores de flujo para obtener el eno distal, en ni\u00f1os asm\u00e1ticos desde lactantes a escolares, adem\u00e1s de espirometr\u00eda forzada, cuestionario de s\u00edntomas e \u00edndice predictivo de asma.Los resultados obtenidos soportan las conclusiones siguientes: – la validez de la medida del eno proximal con medidores port\u00e1tiles, en ni\u00f1os mayores de 5 a\u00f1os de edad, a respiraci\u00f3n \u00fanica y con tiempos espiratorios bajos (6 segundos). – Cuestionario de s\u00edntomas, funci\u00f3n pulmonar y eno, son variables no dependientes en el asma infantil. – En ni\u00f1os menores de dos a\u00f1os de edad, se puede determinar el eno on-line sin sedaci\u00f3n y hay acuerdo con el \u00edndice predictivo de asma. – El eno distal no se correlaciona con el eno proximal.<\/p>\n

 <\/p>\n

Datos acad\u00e9micos de la tesis doctoral \u00ab\u00f3xido n\u00edtrico exhalado y asma: metodolog\u00eda, interpretaci\u00f3n de los resultados y aplicaciones en ni\u00f1os<\/strong>\u00ab<\/h3>\n
    \n
  • T\u00edtulo de la tesis:<\/strong>\u00a0 \u00f3xido n\u00edtrico exhalado y asma: metodolog\u00eda, interpretaci\u00f3n de los resultados y aplicaciones en ni\u00f1os <\/li>\n
  • Autor:<\/strong>\u00a0 Paula Corcuera Elosegui <\/li>\n
  • Universidad:<\/strong>\u00a0 Pa\u00eds vasco\/euskal herriko unibertsitatea<\/li>\n
  • Fecha de lectura de la tesis:<\/strong>\u00a0 31\/05\/2013<\/li>\n<\/ul>\n

     <\/p>\n

    Direcci\u00f3n y tribunal<\/h3>\n
      \n
    • Director de la tesis<\/strong>\n
        \n
      • Jos\u00e9 Javier Korta Murua<\/li>\n<\/ul>\n<\/li>\n
      • Tribunal<\/strong>\n
          \n
        • Presidente del tribunal: Juan Carlos Vitoria cormenzana <\/li>\n
        • f\u00e9lix Lorente toledano (vocal)<\/li>\n
        • Jes\u00fas Argente oliver (vocal)<\/li>\n
        • alfredo Blanco quiros (vocal)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n

           <\/p>\n","protected":false},"excerpt":{"rendered":"

          Tesis doctoral de Paula Corcuera Elosegui El \u00f3xido n\u00edtrico exhalado (eno) es un marcador indirecto de la inflamaci\u00f3n asm\u00e1tica y […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[4275,12909],"tags":[15289,14979,14687,221684,26280,226504],"class_list":["post-114222","post","type-post","status-publish","format-standard","hentry","category-neurociencias","category-pais-vasco-euskal-herriko-unibertsitatea","tag-alfredo-blanco-quiros","tag-felix-lorente-toledano","tag-jesus-argente-oliver","tag-jose-javier-korta-murua","tag-juan-carlos-vitoria-cormenzana","tag-paula-corcuera-elosegui"],"_links":{"self":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/114222","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/comments?post=114222"}],"version-history":[{"count":0,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/114222\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/media?parent=114222"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/categories?post=114222"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/tags?post=114222"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}