{"id":116269,"date":"2014-10-09T00:00:00","date_gmt":"2014-10-09T00:00:00","guid":{"rendered":""},"modified":"2014-10-09T00:00:00","modified_gmt":"2014-10-09T00:00:00","slug":"cellular-and-subcellular-distribution-of-metals-and-metal-nanoparticles-biomarkers-and-histopathology-in-mussels-mytilus-galloprovincialis-exposed-to-engineered-metal-nanoparticles-zno-cds-ag-a","status":"publish","type":"post","link":"https:\/\/www.deberes.net\/tesis\/histologia-animal\/cellular-and-subcellular-distribution-of-metals-and-metal-nanoparticles-biomarkers-and-histopathology-in-mussels-mytilus-galloprovincialis-exposed-to-engineered-metal-nanoparticles-zno-cds-ag-a\/","title":{"rendered":"Cellular and subcellular distribution of metals and metal nanoparticles, biomarkers and histopathology in mussels, mytilus galloprovincialis, exposed to engineered metal nanoparticles (zno, cds, ag, a"},"content":{"rendered":"<h2>Tesis doctoral de <strong> Alba Jimeno Romero <\/strong><\/h2>\n<p>The present work was aimed at identifying the potential risks to the environment posed by engineered nanoparticles by adressing several key questions: (1) how does the environment into which nanoparticles are released affect their physicochemical properties (in terms of solubility, aggregation\u00c2\u00bf)? (2) how does this change their ability to interact with organisms and cells (bioavailability)? (3) does availability result in toxicity in all cases? (4) are bioavailability and toxicity of engineered nanoparticles different to those of their bulk and aqueous counterparts? (5) are biomarkers a suitable tool for the asessment of nanoparticle effects?. With that purpose, experiments were carried out to test the effect of dose and exposure time to tio2, au, zno, ag and cds nps, in comparison to the bulk and aqueous forms of those metals in mussels, mytilus galloprovincialis. As a result, the key factors driving nanoparticle toxicity were identified, and the influence of size, solubility, elementalcomposition, capping agents and additives on bioavailability, cell and tissue distribution, and effects were determined.<\/p>\n<p>&nbsp;<\/p>\n<h3>Datos acad\u00e9micos de la tesis doctoral \u00ab<strong>Cellular and subcellular distribution of metals and metal nanoparticles, biomarkers and histopathology in mussels, mytilus galloprovincialis, exposed to engineered metal nanoparticles (zno, cds, ag, a<\/strong>\u00ab<\/h3>\n<ul>\n<li><strong>T\u00edtulo de la tesis:<\/strong>\u00a0 Cellular and subcellular distribution of metals and metal nanoparticles, biomarkers and histopathology in mussels, mytilus galloprovincialis, exposed to engineered metal nanoparticles (zno, cds, ag, a <\/li>\n<li><strong>Autor:<\/strong>\u00a0 Alba Jimeno Romero <\/li>\n<li><strong>Universidad:<\/strong>\u00a0 Pa\u00eds vasco\/euskal herriko unibertsitatea<\/li>\n<li><strong>Fecha de lectura de la tesis:<\/strong>\u00a0 10\/09\/2014<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h3>Direcci\u00f3n y tribunal<\/h3>\n<ul>\n<li><strong>Director de la tesis<\/strong>\n<ul>\n<li>Manuel Soto Lopez<\/li>\n<\/ul>\n<\/li>\n<li><strong>Tribunal<\/strong>\n<ul>\n<li>Presidente del tribunal: juli\u00e1n Blasco moreno <\/li>\n<li>amparo Torreblanca tamarit (vocal)<\/li>\n<li>Mar\u00eda  joao da anuncia\u00ed\u00a7ao Franco bebianno (vocal)<\/li>\n<li>urtzi Izagirre aramyona (vocal)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tesis doctoral de Alba Jimeno Romero The present work was aimed at identifying the potential risks to the environment posed [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center 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