{"id":117482,"date":"2018-03-11T10:47:03","date_gmt":"2018-03-11T10:47:03","guid":{"rendered":""},"modified":"2018-03-11T10:47:03","modified_gmt":"2018-03-11T10:47:03","slug":"efecto-de-la-combinacion-de-biomoleculas-presentes-en-los-alimentos-acido-linoleico-conjugado-resveratrol-y-quercetina-sobre-la-acumulacion-de-grasa-corporal-effects-of-the-combination-of-biomolecu","status":"publish","type":"post","link":"https:\/\/www.deberes.net\/tesis\/ciencias-de-la-nutricion\/efecto-de-la-combinacion-de-biomoleculas-presentes-en-los-alimentos-acido-linoleico-conjugado-resveratrol-y-quercetina-sobre-la-acumulacion-de-grasa-corporal-effects-of-the-combination-of-biomolecu\/","title":{"rendered":"Efecto de la combinaci\u00f3n de biomol\u00e9culas presentes en los alimentos, \u00e1cido linol\u00e9ico conjugado, resveratrol y quercetina, sobre la acumulaci\u00f3n de grasa corporal\/effects of the combination of biomolecu"},"content":{"rendered":"

Tesis doctoral de Noemi Mercedes Arias Rueda <\/strong><\/h2>\n

Dada la creciente incidencia de obesidad a nivel mundial, el presente trabajo deinvestigaci\u00c2\u00bfn se ha centrado en la b\u00c2\u00bfsqueda de biomol\u00c2\u00bfculas activas presentes en losalimentos, las cuales han demostrado poseer cierta actividad reductora de la grasacorporal, con el objetivo de potenciar su efecto al ser administradas en combinaci\u00c2\u00bfn.Las mol\u00c2\u00bfculas objeto de estudio de esta tesis, el \u00c2\u00bfcido linol\u00c2\u00bfico conjugado (cla), elresveratrol (rsv) y la quercetina (q), han sido administradas en un modelo animal derata wistar alimentado con una dieta obesog\u00c2\u00bfnica comercial.En l\u00c2\u00bfneas generales, se han analizado los efectos de dos combinaciones (rsv+cla yrsv+q) sobre la acumulaci\u00c2\u00bfn de la grasa corporal de los animales tratados. Por ello,esta tesis se ha centrado fundamentalmente en los efectos y mecanismos de acci\u00c2\u00bfnjustificativos de los efectos observados en el tejido adiposo blanco, si bien cabemencionar que se han realizado mediciones en otros \u00c2\u00bfrganos y tejidos como elh\u00c2\u00bfgado, m\u00c2\u00bfsculo, suero y tejido adiposo marr\u00c2\u00bfn.Los resultados de la presente investigaci\u00c2\u00bfn revelan que la combinaci\u00c2\u00bfn de rsv+clano resulta una herramienta \u00c2\u00bftil para tratar la obesidad puesto que los efectosreductores de la grasa corporal ejercidos por cada mol\u00c2\u00bfcula cuando \u00c2\u00bfstas sonadministradas de forma individual desaparecen al ser co-administradas. Por elcontrario, la administraci\u00c2\u00bfn conjunta de rsv+q no solo produce un efecto sin\u00c2\u00bfrgicoen la reducci\u00c2\u00bfn de la grasa corporal sino que adem\u00c2\u00bfs induce una marronizaci\u00c2\u00bfn deltejido adiposo blanco (efecto no descrito previamente para estas biomol\u00c2\u00bfculas) yreduce la esteatosis hep\u00c2\u00bftica. Es por ello que esta \u00c2\u00bfltima combinaci\u00c2\u00bfn resulta unapropuesta \u00c2\u00bftil de ser considerada para el tratamiento y\/o prevenci\u00c2\u00bfn de la obesidad.<\/p>\n

 <\/p>\n

Datos acad\u00e9micos de la tesis doctoral \u00abEfecto de la combinaci\u00f3n de biomol\u00e9culas presentes en los alimentos, \u00e1cido linol\u00e9ico conjugado, resveratrol y quercetina, sobre la acumulaci\u00f3n de grasa corporal\/effects of the combination of biomolecu<\/strong>\u00ab<\/h3>\n
    \n
  • T\u00edtulo de la tesis:<\/strong>\u00a0 Efecto de la combinaci\u00f3n de biomol\u00e9culas presentes en los alimentos, \u00e1cido linol\u00e9ico conjugado, resveratrol y quercetina, sobre la acumulaci\u00f3n de grasa corporal\/effects of the combination of biomolecu <\/li>\n
  • Autor:<\/strong>\u00a0 Noemi Mercedes Arias Rueda <\/li>\n
  • Universidad:<\/strong>\u00a0 Pa\u00eds vasco\/euskal herriko unibertsitatea<\/li>\n
  • Fecha de lectura de la tesis:<\/strong>\u00a0 19\/05\/2015<\/li>\n<\/ul>\n

     <\/p>\n

    Direcci\u00f3n y tribunal<\/h3>\n
      \n
    • Director de la tesis<\/strong>\n
        \n
      • Mar\u00eda Del Puy Portillo Baquedano<\/li>\n<\/ul>\n<\/li>\n
      • Tribunal<\/strong>\n
          \n
        • Presidente del tribunal: catalina Pic\u00f3 segura <\/li>\n
        • Mar\u00eda Jes\u00fas Moreno aliaga (vocal)<\/li>\n
        • leixuri Aguirre lopez (vocal)<\/li>\n
        • christian Carpene — (vocal)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n

           <\/p>\n","protected":false},"excerpt":{"rendered":"

          Tesis doctoral de Noemi Mercedes Arias Rueda Dada la creciente incidencia de obesidad a nivel mundial, el presente trabajo deinvestigaci\u00c2\u00bfn […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[467,12909],"tags":[72068,34330,231465,55797,18190,231464],"class_list":["post-117482","post","type-post","status-publish","format-standard","hentry","category-ciencias-de-la-nutricion","category-pais-vasco-euskal-herriko-unibertsitatea","tag-catalina-pico-segura","tag-christian-carpene","tag-leixuri-aguirre-lopez","tag-maria-del-puy-portillo-baquedano","tag-maria-jesus-moreno-aliaga","tag-noemi-mercedes-arias-rueda"],"_links":{"self":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/117482","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/comments?post=117482"}],"version-history":[{"count":0,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/117482\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/media?parent=117482"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/categories?post=117482"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/tags?post=117482"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}