{"id":117535,"date":"2018-03-11T10:47:08","date_gmt":"2018-03-11T10:47:08","guid":{"rendered":"https:\/\/www.deberes.net\/tesis\/sin-categoria\/evaluacion-histologica-de-la-osteogenesis-inducida-por-flavonoides-en-compararacion-con-otro-estimulador-oseo-en-alveolos-post-extraccion-estudio-experimental-en-perros-american-fox-hound\/"},"modified":"2018-03-11T10:47:08","modified_gmt":"2018-03-11T10:47:08","slug":"evaluacion-histologica-de-la-osteogenesis-inducida-por-flavonoides-en-compararacion-con-otro-estimulador-oseo-en-alveolos-post-extraccion-estudio-experimental-en-perros-american-fox-hound","status":"publish","type":"post","link":"https:\/\/www.deberes.net\/tesis\/estomatologia-y-ortodoncia\/evaluacion-histologica-de-la-osteogenesis-inducida-por-flavonoides-en-compararacion-con-otro-estimulador-oseo-en-alveolos-post-extraccion-estudio-experimental-en-perros-american-fox-hound\/","title":{"rendered":"Evaluaci\u00f3n histol\u00f3gica de la osteog\u00e9nesis inducida por flavonoides en compararaci\u00f3n con otro estimulador \u00f3seo en alveolos post extracci\u00f3n. estudio experimental en perros american fox hound"},"content":{"rendered":"<h2>Tesis doctoral de <strong> Manuel M\u00e1iquez Gos\u00e1lvez <\/strong><\/h2>\n<p>Abstract objective: the aim of this study was to evaluate the effect of topical applications of flavonoids (5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone, sigma-aldrich quimica, s.L.) Compared to other bone stimulator (n-acetyl-5-methoxytryptamine, sigma-aldrich quimica, s.L.) On new bone formation in post-extraction alveoli of american fox hound dogs after 30, 45 and 60 days.   materials and methods: nine american fox hound dogs were used in this study, extracting lower premolars (p2, p3 y p4) and first and second molar (m1, m2). Flavonoids impregnated membranes were applied at p2, m1 and m2 sites in left hemi-mandible. Another bone stimulator impregnated membranes were applied at p2, m1 and m2 sites in right hemi-mandible. Alveoli p3 and p4 sites were used as control sites using no biomaterials on them. Bone biopsies were taken at 30, 45 and 60 days and stained with hematoxylin-eosin and toluidine blue.   results: at 30 days a higher percentage of immature bone was observed in the control group (57.40 \u00c2\u00b1 2.30%) than in the flavonoids (33.18 \u00c2\u00b1 3.15 %) and the other stimulator group (22.9 \u00c2\u00b1 5.91%) with significant differences between the three groups (p&lt;0.05). At 45 days, results were significantly better at bone stimulator sites (9.88 \u00c2\u00b1 1.42%) than flavonoids (18.87 \u00c2\u00b1 4.6%) and control sites (35.3 \u00c2\u00b1 1.23) (p&lt;0.05). At 60 days immature bone percentages were similar for all groups. conclusions: topical applications of either 5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone or n-acetyl-5-methoxytryptamine have a potential to accelerate bone tissue in early healing stages. It would be interesting to extend the number of tests, increasing the number of animals to confirm all these data.  resumen objetivo: el objetivo de este estudio fue evaluar el efecto de la aplicaci\u00f3n t\u00f3pica de flavonoides (5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone, sigma-aldrich quimica, s.L.) Comparado con otro estimulador \u00f3seo (n-acetyl-5-methoxytryptamine, sigma-aldrich quimica, s.L.) En la osteog\u00e9nesis de alveolos post extracci\u00f3n de perros american fox hound despu\u00e9s de 30, 45 y 60 d\u00edas. material y m\u00e9todos: nueve perros american fox hound fueron la fuente de este estudio, extray\u00e9ndoles los premolares inferiores (p2, p3 y p4) y el primer y segundo molar (m1 y m2). Se aplicaron membranas con flavonoides en p2, m1 y m2 en el lado izquierdo. Membranas con otro estimulador \u00f3seo fueron aplicadas en los alveolos p2, m1 y m2 del lado derecho. Los alveolos p3 y p4 fueron utilizados como control, cicatrizando sin biomaterial. Las biopsias de hueso fueron tomadas a los 30, 45 y 60 d\u00edas y se ti\u00f1eron con hematoxilina-eosina y azul de toluidina. resultados: a los 30 d\u00edas, el grupo control present\u00f3 un porcentaje m\u00e1s elevado de hueso inmaduro (57.40 \u00c2\u00b1 2.30%) que en el grupo tratado con flavonoides (33.18 \u00c2\u00b1 3.15 %) y con otro estimulador \u00f3seo (22.9 \u00c2\u00b1 5.91%) con diferencias significativas entre los tres grupos (p&lt;0.05). A los 45 d\u00edas, los resultados fueron significativamente mejores en los alveolos tratados con otro estimulador \u00f3seo (9.88 \u00c2\u00b1 1.42%) comparado con los alveolos de flavonoides (18.87 \u00c2\u00b1 4.6%) y con el grupo control cicatrizado sin biomaterial (35.3 \u00c2\u00b1 1.23) (p&lt;0.05). A los 60 d\u00edas, la cantidad de hueso inmaduro fue pr\u00e1cticamente similar para todos los grupos. conclusiones: la aplicaci\u00f3n t\u00f3pica, tanto de 5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone como de n-acetyl-5-methoxytryptamine, tiene la capacidad de acelerar la formaci\u00f3n de hueso en los estadios tempranos de la cicatrizaci\u00f3n \u00f3sea. Ser\u00eda interesante ampliar el n\u00famero de estudios, incrementando el n\u00famero de animales para confirmar todos estos datos.<\/p>\n<p>&nbsp;<\/p>\n<h3>Datos acad\u00e9micos de la tesis doctoral \u00ab<strong>Evaluaci\u00f3n histol\u00f3gica de la osteog\u00e9nesis inducida por flavonoides en compararaci\u00f3n con otro estimulador \u00f3seo en alveolos post extracci\u00f3n. estudio experimental en perros american fox hound<\/strong>\u00ab<\/h3>\n<ul>\n<li><strong>T\u00edtulo de la tesis:<\/strong>\u00a0 Evaluaci\u00f3n histol\u00f3gica de la osteog\u00e9nesis inducida por flavonoides en compararaci\u00f3n con otro estimulador \u00f3seo en alveolos post extracci\u00f3n. estudio experimental en perros american fox hound <\/li>\n<li><strong>Autor:<\/strong>\u00a0 Manuel M\u00e1iquez Gos\u00e1lvez <\/li>\n<li><strong>Universidad:<\/strong>\u00a0 Murcia<\/li>\n<li><strong>Fecha de lectura de la tesis:<\/strong>\u00a0 29\/05\/2015<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h3>Direcci\u00f3n y tribunal<\/h3>\n<ul>\n<li><strong>Director de la tesis<\/strong>\n<ul>\n<li>Jos\u00e9 Luis Calvo Guirado<\/li>\n<\/ul>\n<\/li>\n<li><strong>Tribunal<\/strong>\n<ul>\n<li>Presidente del tribunal: gerardo G\u00f3mez moreno <\/li>\n<li>Mar\u00eda piedad Ram\u00edrez fern\u00e1ndez (vocal)<\/li>\n<li>Javier Guardia mu\u00f1oz (vocal)<\/li>\n<li>Antonio Aguilar-salvatierra raya (vocal)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tesis doctoral de Manuel M\u00e1iquez Gos\u00e1lvez Abstract objective: the aim of this study was to evaluate the effect of topical 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