{"id":135679,"date":"1997-01-01T00:00:00","date_gmt":"1997-01-01T00:00:00","guid":{"rendered":"https:\/\/www.deberes.net\/tesis\/sin-categoria\/determinacion-inmunohistoquimica-de-oncoproteinas-en-el-carcinoma-vesical-de-celulas-transicionales-su-significado-anatomoclinico\/"},"modified":"1997-01-01T00:00:00","modified_gmt":"1997-01-01T00:00:00","slug":"determinacion-inmunohistoquimica-de-oncoproteinas-en-el-carcinoma-vesical-de-celulas-transicionales-su-significado-anatomoclinico","status":"publish","type":"post","link":"https:\/\/www.deberes.net\/tesis\/ciencias-medicas\/determinacion-inmunohistoquimica-de-oncoproteinas-en-el-carcinoma-vesical-de-celulas-transicionales-su-significado-anatomoclinico\/","title":{"rendered":"Determinacion inmunohistoquimica de oncoproteinas en el carcinoma vesical de celulas transicionales: su significado anatomoclinico."},"content":{"rendered":"

Tesis doctoral de Blasco Alfonso Jos\u00e9 Enrique <\/strong><\/h2>\n

Puesto que el carcinoma vesical de celulas transicionales constituye un problema oncologico de primer orden por su incidencia en aumento y su probada agresividad en muchos casos, hemos querido con esta tesis contribuir al conocimiento de nuevos factores pronosticos en base a la determinacion inmunohistoquimica de oncoproteinas (p53,rb,c-erbb-2) que la literatura describe como implicadas en esta patolog\u00eda.Ademas hemos querido ratificar la importancia de ciertos parametros macroscopicos y microscopicos tumorales asi como de la anamnesis.Para ello hemos estudiado un total de 64 tumores primarios de vejiga superficiales e infiltrantes de los cuales el 87,5% fueron varones y con una edad media de 68,3 a\u00f1os. El tiempo de seguimiento ha sido de 30 meses. tras este estudio hemos concluido que: -la presencia de p53 en el tumor se asocia de forma significativa a tumores infiltrantes y agresivos. – los carcinomas uroteliales son inmunohistoquimicamente positivos frente a la proteina rb y expresan su forma alterada en un porcentaje bajo. – la oncoproteina c-erbb-2 se expresa intensamente en el carcinoma vesical superficial aunque carece de capacidad predictiva para se\u00f1alar recurrencia o progresion. – parametros como el tama\u00f1o de la base tumoral, la papilaridad, el grado el estadio, el sexo y el habito tabaquico se hallan fuertemente implicados en la evolucion y pronostico de estos tumores.<\/p>\n

 <\/p>\n

Datos acad\u00e9micos de la tesis doctoral \u00abDeterminacion inmunohistoquimica de oncoproteinas en el carcinoma vesical de celulas transicionales: su significado anatomoclinico.<\/strong>\u00ab<\/h3>\n
    \n
  • T\u00edtulo de la tesis:<\/strong>\u00a0 Determinacion inmunohistoquimica de oncoproteinas en el carcinoma vesical de celulas transicionales: su significado anatomoclinico. <\/li>\n
  • Autor:<\/strong>\u00a0 Blasco Alfonso Jos\u00e9 Enrique <\/li>\n
  • Universidad:<\/strong>\u00a0 Universitat de val\u00e9ncia (estudi general)<\/li>\n
  • Fecha de lectura de la tesis:<\/strong>\u00a0 01\/01\/1997<\/li>\n<\/ul>\n

     <\/p>\n

    Direcci\u00f3n y tribunal<\/h3>\n
      \n
    • Director de la tesis<\/strong>\n
        \n
      • Antonio Llombart Bosch<\/li>\n<\/ul>\n<\/li>\n
      • Tribunal<\/strong>\n
          \n
        • Presidente del tribunal: Amando Peydro Olaya <\/li>\n
        • Alfredo Tramoyeres Celma (vocal)<\/li>\n
        • Julio Zaragoza Orts (vocal)<\/li>\n
        • Ferran Algaba Arrea (vocal)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n

           <\/p>\n","protected":false},"excerpt":{"rendered":"

          Tesis doctoral de Blasco Alfonso Jos\u00e9 Enrique Puesto que el carcinoma vesical de celulas transicionales constituye un problema oncologico de […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[155,9,1027,156,971],"tags":[95276,26963,12285,249940,84107,82989],"class_list":["post-135679","post","type-post","status-publish","format-standard","hentry","category-ciencias-clinicas","category-ciencias-medicas","category-oncologia","category-patologia","category-urologia","tag-alfredo-tramoyeres-celma","tag-amando-peydro-olaya","tag-antonio-llombart-bosch","tag-blasco-alfonso-jose-enrique","tag-ferran-algaba-arrea","tag-julio-zaragoza-orts"],"_links":{"self":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/135679","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/comments?post=135679"}],"version-history":[{"count":0,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/135679\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/media?parent=135679"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/categories?post=135679"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/tags?post=135679"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}