{"id":139466,"date":"2026-01-12T17:45:54","date_gmt":"2026-01-12T17:45:54","guid":{"rendered":"https:\/\/www.deberes.net\/tesis\/sin-categoria\/influencia-del-etanol-y-otros-nutrientes-sobre-la-toxicidad-de-las-sales-ferrosas-en-el-tracto-gastrointestinal-mediada-por-radicales-libres\/"},"modified":"2026-01-12T17:45:54","modified_gmt":"2026-01-12T17:45:54","slug":"influencia-del-etanol-y-otros-nutrientes-sobre-la-toxicidad-de-las-sales-ferrosas-en-el-tracto-gastrointestinal-mediada-por-radicales-libres","status":"publish","type":"post","link":"https:\/\/www.deberes.net\/tesis\/ciencias-medicas\/influencia-del-etanol-y-otros-nutrientes-sobre-la-toxicidad-de-las-sales-ferrosas-en-el-tracto-gastrointestinal-mediada-por-radicales-libres\/","title":{"rendered":"Influencia del etanol y otros nutrientes sobre la toxicidad de las sales ferrosas en el tracto gastrointestinal mediada por radicales libres."},"content":{"rendered":"

Tesis doctoral de Rosa Roldan Ortega <\/strong><\/h2>\n

Los radicales libres generados tras la administracion oral de preparados farmaceuticos que contienen sales ferrosas, pueden provocar la aparicion de patolog\u00eda gastrointestinal. La alta preValencia del consumo de alcohol y del consumo de esos preparados puede modificar su accion lesiva cuando se asocian. Asi mismo, los nutrientes pueden cambiar su perfil lesivo. Este trabajo se divide en dos partes: 1.- Estudio de la cinetica de produccion de radicales libres \u00abin vitro\u00bb, en jugo gastrico, humano, tras la administracion de sales ferrosas y acido ascorbico junto a etanol y nutrientes. 2.- Establecer la toxicidad \u00abin vitro\u00bb de los radicales libres generados en la mucosa gastroduodenal de ratas tras la administracion oral de sales ferrosas y acido ascorbico junto con etanol, mediante estudio anatomopatologico. Y los resultados obtenidos son: – la produccion de radicales libres en jugo gastrico humano tras la administracion de sales ferrosas junto con alcohol o nutrientes, esta en intima relacion con el ph del medio, siendo maxima a menor ph. La presencia de etanol y de nutrientes determina una disminucion significativa de los radicales libres cuantificables en el medio, siendo el etanol de entre las sustancias estudiadas el que la limita en mayor proporcion. – en el estudio estructural y ultraestructural de mucosa gastroduodenal de ratas tratadas con sales ferrosas, acido ascorbico y\/o etanol, aparecen lesiones reversibles, sobre todo en mucosa gastrica.<\/p>\n

 <\/p>\n

Datos acad\u00e9micos de la tesis doctoral \u00abInfluencia del etanol y otros nutrientes sobre la toxicidad de las sales ferrosas en el tracto gastrointestinal mediada por radicales libres.<\/strong>\u00ab<\/h3>\n
    \n
  • T\u00edtulo de la tesis:<\/strong>\u00a0 Influencia del etanol y otros nutrientes sobre la toxicidad de las sales ferrosas en el tracto gastrointestinal mediada por radicales libres. <\/li>\n
  • Autor:<\/strong>\u00a0 Rosa Roldan Ortega <\/li>\n
  • Universidad:<\/strong>\u00a0 Murcia<\/li>\n
  • Fecha de lectura de la tesis:<\/strong>\u00a0 01\/01\/1992<\/li>\n<\/ul>\n

     <\/p>\n

    Direcci\u00f3n y tribunal<\/h3>\n
      \n
    • Director de la tesis<\/strong>\n
        \n
      • Aurelio Luna Maldonado<\/li>\n<\/ul>\n<\/li>\n
      • Tribunal<\/strong>\n
          \n
        • Presidente del tribunal: Gisbert Calabuig Juan Antonio <\/li>\n
        • Francisco Sanchez Bueno (vocal)<\/li>\n
        • Fernando Espi Martinez (vocal)<\/li>\n
        • Sanchez Garcia Jos\u00e9 Antonio (vocal)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n

           <\/p>\n","protected":false},"excerpt":{"rendered":"

          Tesis doctoral de Rosa Roldan Ortega Los radicales libres generados tras la administracion oral de preparados farmaceuticos que contienen sales […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[339,9,957,8235,401],"tags":[3274,8440,8254,11390,253973,8472],"class_list":["post-139466","post","type-post","status-publish","format-standard","hentry","category-analisis-de-farmacos","category-ciencias-medicas","category-farmacologia","category-murcia","category-toxicologia","tag-aurelio-luna-maldonado","tag-fernando-espi-Martinez","tag-francisco-sanchez-bueno","tag-gisbert-calabuig-juan-antonio","tag-rosa-roldan-ortega","tag-sanchez-garcia-jose-antonio"],"_links":{"self":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/139466","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/comments?post=139466"}],"version-history":[{"count":0,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/139466\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/media?parent=139466"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/categories?post=139466"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/tags?post=139466"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}