{"id":140211,"date":"2026-01-12T17:52:30","date_gmt":"2026-01-12T17:52:30","guid":{"rendered":"https:\/\/www.deberes.net\/tesis\/sin-categoria\/regulacion-del-sistema-l-de-transporte-de-aminoacidos-por-deprivacion-de-sustrato-en-cultivos-celulares-de-hamster-linea-celular-cho-k1\/"},"modified":"2026-01-12T17:52:30","modified_gmt":"2026-01-12T17:52:30","slug":"regulacion-del-sistema-l-de-transporte-de-aminoacidos-por-deprivacion-de-sustrato-en-cultivos-celulares-de-hamster-linea-celular-cho-k1","status":"publish","type":"post","link":"https:\/\/www.deberes.net\/tesis\/quimica\/regulacion-del-sistema-l-de-transporte-de-aminoacidos-por-deprivacion-de-sustrato-en-cultivos-celulares-de-hamster-linea-celular-cho-k1\/","title":{"rendered":"Regulacion del sistema l de transporte de aminoacidos por deprivacion de sustrato en cultivos celulares de hamster (linea celular cho-k1)."},"content":{"rendered":"<h2>Tesis doctoral de <strong>  Valentin Cid Francisco Javier <\/strong><\/h2>\n<p>En este trabajo se ha caracterizado la regulacion del sistema l de transporte de aminoacidos en la linea celular de hamster cho-k1, por la disponibilidad de leucina en el medio de cultivo. Cuando las celulas se incuban en medio carente de leucina la actividad del sistema l se estimula, incrementando tanto su velocidad inicial de captacion como su capacidad de acumular sustratos en el interior de las celulas al estado estacionario.  la activacion del sistema l se independiente de sintesis de proteinas y dependiente de la sintesis de rna.  se concluye que la deprivacion de leucina modifica las propiedades cineticas del sistema l, incrementando su capacidad de acumular sustratos, sin aumento del numero de transportadores.  nuestros resultados, por otra parte son consistentes con que el efector de estos cambios sea el nivel intracelular de leucil-trna.<\/p>\n<p>&nbsp;<\/p>\n<h3>Datos acad\u00e9micos de la tesis doctoral \u00ab<strong>Regulacion del sistema l de transporte de aminoacidos por deprivacion de sustrato en cultivos celulares de hamster (linea celular cho-k1).<\/strong>\u00ab<\/h3>\n<ul>\n<li><strong>T\u00edtulo de la tesis:<\/strong>\u00a0 Regulacion del sistema l de transporte de aminoacidos por deprivacion de sustrato en cultivos celulares de hamster (linea celular cho-k1). <\/li>\n<li><strong>Autor:<\/strong>\u00a0  Valentin Cid Francisco Javier <\/li>\n<li><strong>Universidad:<\/strong>\u00a0 Valladolid<\/li>\n<li><strong>Fecha de lectura de la tesis:<\/strong>\u00a0 01\/01\/1992<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h3>Direcci\u00f3n y tribunal<\/h3>\n<ul>\n<li><strong>Director de la tesis<\/strong>\n<ul>\n<li> Dominguez Lobato M. Carmen<\/li>\n<\/ul>\n<\/li>\n<li><strong>Tribunal<\/strong>\n<ul>\n<li>Presidente del tribunal: Benito Herreros Fernandez <\/li>\n<li>Mar\u00ed\u00a7al Pastor Anglada (vocal)<\/li>\n<li> Gunther Nonell M. Antonia (vocal)<\/li>\n<li>Alfredo Moreno Diaz-calderon (vocal)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tesis doctoral de Valentin Cid Francisco Javier En este trabajo se ha caracterizado la regulacion del sistema l de transporte [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[160,115,35,817,17,12451],"tags":[254782,12641,254781,110578,12645,254780],"class_list":["post-140211","post","type-post","status-publish","format-standard","hentry","category-bioquimica","category-bioquimica-molecular","category-ciencias-de-la-vida","category-fisiologia-humana","category-quimica","category-valladolid","tag-alfredo-moreno-diaz-calderon","tag-benito-herreros-fernandez","tag-dominguez-lobato-m-carmen","tag-gunther-nonell-m-antonia","tag-marial-pastor-anglada","tag-valentin-cid-francisco-javier"],"_links":{"self":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/140211","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/comments?post=140211"}],"version-history":[{"count":0,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/140211\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/media?parent=140211"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/categories?post=140211"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/tags?post=140211"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}