{"id":25421,"date":"2018-03-09T09:16:48","date_gmt":"2018-03-09T09:16:48","guid":{"rendered":"https:\/\/www.deberes.net\/tesis\/sin-categoria\/estudio-caso-control-genotipo-gstm1o-gstt1o-ctpsdgsxn-fenotipo-nat2-y-actividad-xo-y-su-influencia-en-el-riesgo-de-cancer-de-laringe-en-fumadores\/"},"modified":"2018-03-09T09:16:48","modified_gmt":"2018-03-09T09:16:48","slug":"estudio-caso-control-genotipo-gstm1o-gstt1o-ctpsdgsxn-fenotipo-nat2-y-actividad-xo-y-su-influencia-en-el-riesgo-de-cancer-de-laringe-en-fumadores","status":"publish","type":"post","link":"https:\/\/www.deberes.net\/tesis\/zaragoza\/estudio-caso-control-genotipo-gstm1o-gstt1o-ctpsdgsxn-fenotipo-nat2-y-actividad-xo-y-su-influencia-en-el-riesgo-de-cancer-de-laringe-en-fumadores\/","title":{"rendered":"Estudio caso-control: genotipo gstm1*o, gstt1*o, ctpsdg*sxn, fenotipo nat2 y actividad xo y su influencia en el riesgo de c\u00e1ncer de laringe en fumadores"},"content":{"rendered":"<h2>Tesis doctoral de <strong>  Mart\u00ednez Sub\u00edas Jos\u00e9 Javier <\/strong><\/h2>\n<p>El genotipo gstm1 nulo, que representa una menor capacidad detoxificadora de diferentes carcin\u00f3genos, al igual que el genotipo gstt1 nulo no influyen de forma aisada como factor de riesgo para el desarrollo de c\u00e1cer de laringe.  el genotipo cyp2dg*2xn que corresponde a una capacidad hidroxiladora ultrarr\u00e1pida presenta una mayor presencia en el caso de sujetos con carcinoma de laringe que en la poblaci\u00f3n control, aumentando el riesgo en 3,67 veces de padecer c\u00e1ncer de laringe.  el fenotipo acetilador nat2 no influye en el desarrollo de carcinoma lar\u00edngeo en individuos fumadores ni influye en la localizaci\u00f3n del tumor.<\/p>\n<p>&nbsp;<\/p>\n<h3>Datos acad\u00e9micos de la tesis doctoral \u00ab<strong>Estudio caso-control: genotipo gstm1*o, gstt1*o, ctpsdg*sxn, fenotipo nat2 y actividad xo y su influencia en el riesgo de c\u00e1ncer de laringe en fumadores<\/strong>\u00ab<\/h3>\n<ul>\n<li><strong>T\u00edtulo de la tesis:<\/strong>\u00a0 Estudio caso-control: genotipo gstm1*o, gstt1*o, ctpsdg*sxn, fenotipo nat2 y actividad xo y su influencia en el riesgo de c\u00e1ncer de laringe en fumadores <\/li>\n<li><strong>Autor:<\/strong>\u00a0  Mart\u00ednez Sub\u00edas Jos\u00e9 Javier <\/li>\n<li><strong>Universidad:<\/strong>\u00a0 Zaragoza<\/li>\n<li><strong>Fecha de lectura de la tesis:<\/strong>\u00a0 16\/09\/2003<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h3>Direcci\u00f3n y tribunal<\/h3>\n<ul>\n<li><strong>Director de la tesis<\/strong>\n<ul>\n<li>Blanca Sinues Porta<\/li>\n<\/ul>\n<\/li>\n<li><strong>Tribunal<\/strong>\n<ul>\n<li>Presidente del tribunal: blanca Conde guerri <\/li>\n<li>hugo Lia\u00f1o mart\u00ednez (vocal)<\/li>\n<li>Jos\u00e9 Traserra paradeda (vocal)<\/li>\n<li> Garc\u00eda de jal\u00f3n comet \u00e1ngel (vocal)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tesis doctoral de Mart\u00ednez Sub\u00edas Jos\u00e9 Javier El genotipo gstm1 nulo, que representa una menor capacidad detoxificadora de diferentes carcin\u00f3genos, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center 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