{"id":34630,"date":"1998-01-01T00:00:00","date_gmt":"1998-01-01T00:00:00","guid":{"rendered":"https:\/\/www.deberes.net\/tesis\/sin-categoria\/evaluacion-electrofisiologica-de-la-eficacia-de-propafenona-en-el-tratamiento-de-las-arritmias-ventriculares-sostenidas\/"},"modified":"1998-01-01T00:00:00","modified_gmt":"1998-01-01T00:00:00","slug":"evaluacion-electrofisiologica-de-la-eficacia-de-propafenona-en-el-tratamiento-de-las-arritmias-ventriculares-sostenidas","status":"publish","type":"post","link":"https:\/\/www.deberes.net\/tesis\/ciencias-medicas\/evaluacion-electrofisiologica-de-la-eficacia-de-propafenona-en-el-tratamiento-de-las-arritmias-ventriculares-sostenidas\/","title":{"rendered":"Evaluacion electrofisiologica de la eficacia de propafenona en el tratamiento de las arritmias ventriculares sostenidas."},"content":{"rendered":"

Tesis doctoral de Rodriguez Tejero Isidoro Adolfo <\/strong><\/h2>\n

El prop\u00f3sito de esta tesis fu\u00e9 analizar el efecto que la administraci\u00f3n i.V. De propafenona (p), antiarr\u00edtmico de clase ic (seg\u00fan la clasificaci\u00f3n de vaughan-williams), tiene sobre los par\u00e1metros electrofisiol\u00f3gicos (ef) del automatismo y la conducci\u00f3n; conocer la protecci\u00f3n que p ofrece frente a la inducibilidad de la arritmia ventricular mediante electro estimulaci\u00f3n programada (eep); determinar los posibles efectos delet\u00e9reos que p ejerce sobre los par\u00e1metros ef y determinar la tolerancia hemodinamica al f\u00e1rmaco. para ello se estudiaron de forma prospectiva 21 pacientes con arritmias ventriculares sostenidas (tv monomorfa sostenida, tv sincopal y fibrilaci\u00f3n ventricular) cl\u00ednicamente documentadas en todos los casos. A todos ellos se les realiz\u00f3 un estudio hemodin\u00e1mico previo con ventriculograf\u00eda izquierda y angiograf\u00eda coronaria. posteriormente, se realiz\u00f3 eef basal (tras retirar toda la medicaci\u00f3n antiarr\u00edtmica al menos 5 vidas medias y 3 meses en el caso de amiodarona) con 2 longitudes de ciclo distintas (600 y 450 ms) y hasta con 3 extraest\u00edmulos en caso de ser necesario, hasta desencadenar tv estudi\u00e1ndose sus caracter\u00edsticas. Una vez revertido el paciente a ritmo sinusal, se administraban 2,5 mg\/kg de peso de p i.V. En 10 minutos, repiti\u00e9ndose nuevamente todo el protocolo anteriormente mencionado. se obtuvieron las siguientes conclusiones: 1) la administraci\u00f3n i.V. De p enlentece la velocidad de conducci\u00f3n intranodal, en el sistema de his-purkinje e intraventricular, siendo dicho efecto frecuencia-dependiente. La longitud de ciclo basal y el qt se prolongaron ligeramente sin alcanzar significaci\u00f3n estad\u00edstica. 2) p control\u00f3 eficazmente la arritmia ventricular en el 38% de los pacientes. 3) en el 19% de casos, p determin\u00f3 la aparici\u00f3n de arritmogenia, demostr\u00e1ndose mayor asociaci\u00f3n con fracci\u00f3n de eyecci\u00f3n (fe) menor del 40%, clase funcional iii \u00f3 iv de la nyha, presencia d<\/p>\n

 <\/p>\n

Datos acad\u00e9micos de la tesis doctoral \u00abEvaluacion electrofisiologica de la eficacia de propafenona en el tratamiento de las arritmias ventriculares sostenidas.<\/strong>\u00ab<\/h3>\n
    \n
  • T\u00edtulo de la tesis:<\/strong>\u00a0 Evaluacion electrofisiologica de la eficacia de propafenona en el tratamiento de las arritmias ventriculares sostenidas. <\/li>\n
  • Autor:<\/strong>\u00a0 Rodriguez Tejero Isidoro Adolfo <\/li>\n
  • Universidad:<\/strong>\u00a0 Complutense de Madrid<\/li>\n
  • Fecha de lectura de la tesis:<\/strong>\u00a0 01\/01\/1998<\/li>\n<\/ul>\n

     <\/p>\n

    Direcci\u00f3n y tribunal<\/h3>\n
      \n
    • Director de la tesis<\/strong>\n
        \n
      • Concepcion Moro Serrano<\/li>\n<\/ul>\n<\/li>\n
      • Tribunal<\/strong>\n
          \n
        • Presidente del tribunal: Pedro Zarco Gutierrez <\/li>\n
        • Melchor Alvarez De Mon Soto (vocal)<\/li>\n
        • Ramon Perez Maestu (vocal)<\/li>\n
        • Manuel Gomis Gavilan (vocal)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n

           <\/p>\n","protected":false},"excerpt":{"rendered":"

          Tesis doctoral de Rodriguez Tejero Isidoro Adolfo El prop\u00f3sito de esta tesis fu\u00e9 analizar el efecto que la administraci\u00f3n i.V. […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[932,9,139],"tags":[29835,23152,14431,7413,14279,93252],"class_list":["post-34630","post","type-post","status-publish","format-standard","hentry","category-cardiologia","category-ciencias-medicas","category-medicina-interna","tag-concepcion-moro-serrano","tag-manuel-gomis-gavilan","tag-melchor-alvarez-de-mon-soto","tag-pedro-zarco-gutierrez","tag-ramon-perez-maestu","tag-rodriguez-tejero-isidoro-adolfo"],"_links":{"self":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/34630","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/comments?post=34630"}],"version-history":[{"count":0,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/34630\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/media?parent=34630"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/categories?post=34630"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/tags?post=34630"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}