{"id":41641,"date":"1999-01-01T00:00:00","date_gmt":"1999-01-01T00:00:00","guid":{"rendered":"https:\/\/www.deberes.net\/tesis\/sin-categoria\/mecanismos-fisiopalogicos-de-la-litiasis-renal-oxalocalcica-en-la-enfermedad-de-crohn\/"},"modified":"1999-01-01T00:00:00","modified_gmt":"1999-01-01T00:00:00","slug":"mecanismos-fisiopalogicos-de-la-litiasis-renal-oxalocalcica-en-la-enfermedad-de-crohn","status":"publish","type":"post","link":"https:\/\/www.deberes.net\/tesis\/ciencias-medicas\/mecanismos-fisiopalogicos-de-la-litiasis-renal-oxalocalcica-en-la-enfermedad-de-crohn\/","title":{"rendered":"Mecanismos fisiopalogicos de la litiasis renal oxalocalcica en la enfermedad de crohn."},"content":{"rendered":"

Tesis doctoral de Antonio Bu\u00f1o Soto <\/strong><\/h2>\n

La preValencia de litiasis renal en pacientes con eiic es superior a la encontrada en la poblaci\u00f3n sana y la composici\u00f3n de los c\u00e1lculos es mayoritariamente de oxalato c\u00e1lcico. en pacientes con eiic y malabsorci\u00f3n intestinal se ha documentado un incremento de la excreci\u00f3n urinaria de oxalato que ha sido considerado como el factor de riesgo litog\u00e9nico cardinal. En este estudio investigamos los factores de riesgo para litiasis renal oxaloc\u00e1lcica en 42 pacientes con enfermedad de crohn y la influencia que sobre ellos ejerce la presencia de actividad de la enfermedad y la participaci\u00f3n de \u00edleon en el proceso patol\u00f3gico. Los resultados del estudio se compararon con los obtenidos en 18 sujetos sanos. Para ello estudiamos la excreci\u00f3n y concentraci\u00f3n en la orina de 24 horas de los compuestos que determinan la litog\u00e9nesis oxaloc\u00e1lcica, la absorci\u00f3n intestinal y oxalato y la actividad intestinal degradadora de oxalato. con respecto al grupo control, los pacientes con enfermedad de crohn exhib\u00edan un descenso muy llamativo del volumen urinario, mayor acidez de la orina y una menor eliminaci\u00f3n urinaria de sodio, citrato, magnesio y sulfato. El descenso de la diuresis obervado en los pacientes determin\u00f3 un incremento significativo de la concentraci\u00f3n de oxalato, fosfato, oxalato c\u00e1lcico, \u00e1cido \u00farico dihidrogenado y brushita. De acuerdo con estos hallazgos la orina de estos pacientes se encontr\u00f3 sobresaturada con respecto a las tres sales litog\u00e9nicas. Los pacientes que fueron estudiados en fase de actividad mostraron mayor sobresaturaci\u00f3n urinaria con respecto al oxalato c\u00e1lcico y a la brushita que los enfermos en fase de no actividad. No hubo diferencias apreciables entre los pacientes con y sin afectaci\u00f3n lineal. el an\u00e1lisis individualizado de los factores de riesgo revel\u00f3 que en esta serie s\u00f3lo dos pacientes no mostraban anomal\u00edas metab\u00f3licas litog\u00e9nicas. Un paciente evidenci\u00f3 una diuresis escasa como \u00fanic<\/p>\n

 <\/p>\n

Datos acad\u00e9micos de la tesis doctoral \u00abMecanismos fisiopalogicos de la litiasis renal oxalocalcica en la enfermedad de crohn.<\/strong>\u00ab<\/h3>\n
    \n
  • T\u00edtulo de la tesis:<\/strong>\u00a0 Mecanismos fisiopalogicos de la litiasis renal oxalocalcica en la enfermedad de crohn. <\/li>\n
  • Autor:<\/strong>\u00a0 Antonio Bu\u00f1o Soto <\/li>\n
  • Universidad:<\/strong>\u00a0 Aut\u00f3noma de Madrid<\/li>\n
  • Fecha de lectura de la tesis:<\/strong>\u00a0 01\/01\/1999<\/li>\n<\/ul>\n

     <\/p>\n

    Direcci\u00f3n y tribunal<\/h3>\n
      \n
    • Director de la tesis<\/strong>\n
        \n
      • Agustin Montero Garcia<\/li>\n<\/ul>\n<\/li>\n
      • Tribunal<\/strong>\n
          \n
        • Presidente del tribunal: Juan jos\u00e9 V\u00e1zquez rodr\u00edguez <\/li>\n
        • Jos\u00e9 Prieto prieto (vocal)<\/li>\n
        • Martinez pineiro carames Jos\u00e9 Antonio (vocal)<\/li>\n
        • arturo Ortiz gonzalez (vocal)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n

           <\/p>\n","protected":false},"excerpt":{"rendered":"

          Tesis doctoral de Antonio Bu\u00f1o Soto La preValencia de litiasis renal en pacientes con eiic es superior a la encontrada […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[9,491,139,179],"tags":[86672,105334,14927,3474,4860,105335],"class_list":["post-41641","post","type-post","status-publish","format-standard","hentry","category-ciencias-medicas","category-gastroenterologia","category-medicina-interna","category-nefrologia","tag-agustin-montero-garcia","tag-antonio-buno-soto","tag-arturo-ortiz-gonzalez","tag-jose-prieto-prieto","tag-juan-jose-vazquez-rodriguez","tag-Martinez-pineiro-carames-jose-antonio"],"_links":{"self":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/41641","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/comments?post=41641"}],"version-history":[{"count":0,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/41641\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/media?parent=41641"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/categories?post=41641"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/tags?post=41641"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}