{"id":56033,"date":"2018-03-09T22:43:43","date_gmt":"2018-03-09T22:43:43","guid":{"rendered":"https:\/\/www.deberes.net\/tesis\/sin-categoria\/determinantes-geneticos-y-dinamica-de-la-respuesta-al-metotrexato-en-celulas-de-cancer-colorrectal\/"},"modified":"2018-03-09T22:43:43","modified_gmt":"2018-03-09T22:43:43","slug":"determinantes-geneticos-y-dinamica-de-la-respuesta-al-metotrexato-en-celulas-de-cancer-colorrectal","status":"publish","type":"post","link":"https:\/\/www.deberes.net\/tesis\/barcelona\/determinantes-geneticos-y-dinamica-de-la-respuesta-al-metotrexato-en-celulas-de-cancer-colorrectal\/","title":{"rendered":"Determinantes geneticos y dinamica de la respuesta al metotrexato en c\u00e9lulas de c\u00e1ncer colorrectal"},"content":{"rendered":"<h2>Tesis doctoral de <strong> Cristina Morales Torres <\/strong><\/h2>\n<p>Studio de la din\u00e1mica de respuesta de c\u00e9lulas de c\u00e1ncer colorrectal al tratamiento selectivo con concentraciones crecientes de metotrexato, caracterizando la formaci\u00f3n de amplic\u00f3n \u00abde novo\u00bb de la dhfr en 5q14.1, delimitando los puntos de rotura del amplic\u00f3n y los mecanismos responsables del proceso de formaci\u00f3n del amplic\u00f3n. Finalmente estudiamos la sensibilidad de c\u00e9lulas resistentes al metotrexato, al propio f\u00e1rmaco<\/p>\n<p>&nbsp;<\/p>\n<h3>Datos acad\u00e9micos de la tesis doctoral \u00ab<strong>Determinantes geneticos y dinamica de la respuesta al metotrexato en c\u00e9lulas de c\u00e1ncer colorrectal<\/strong>\u00ab<\/h3>\n<ul>\n<li><strong>T\u00edtulo de la tesis:<\/strong>\u00a0 Determinantes geneticos y dinamica de la respuesta al metotrexato en c\u00e9lulas de c\u00e1ncer colorrectal <\/li>\n<li><strong>Autor:<\/strong>\u00a0 Cristina Morales Torres <\/li>\n<li><strong>Universidad:<\/strong>\u00a0 Barcelona<\/li>\n<li><strong>Fecha de lectura de la tesis:<\/strong>\u00a0 14\/12\/2006<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h3>Direcci\u00f3n y tribunal<\/h3>\n<ul>\n<li><strong>Director de la tesis<\/strong>\n<ul>\n<li>Miguel Angel Peinado Morales<\/li>\n<\/ul>\n<\/li>\n<li><strong>Tribunal<\/strong>\n<ul>\n<li>Presidente del tribunal: Luis Serra <\/li>\n<li>xavier Mayol (vocal)<\/li>\n<li>gabriel Capella munar (vocal)<\/li>\n<li>silvia Be\u00e1 (vocal)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tesis doctoral de Cristina Morales Torres Studio de la din\u00e1mica de respuesta de c\u00e9lulas de c\u00e1ncer colorrectal al tratamiento selectivo [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center 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