{"id":59187,"date":"2018-03-09T22:47:03","date_gmt":"2018-03-09T22:47:03","guid":{"rendered":"https:\/\/www.deberes.net\/tesis\/sin-categoria\/influencia-de-la-lesion-endotelial-en-el-pronostico-del-ictus-isquemico\/"},"modified":"2018-03-09T22:47:03","modified_gmt":"2018-03-09T22:47:03","slug":"influencia-de-la-lesion-endotelial-en-el-pronostico-del-ictus-isquemico","status":"publish","type":"post","link":"https:\/\/www.deberes.net\/tesis\/santiago-de-compostela\/influencia-de-la-lesion-endotelial-en-el-pronostico-del-ictus-isquemico\/","title":{"rendered":"Influencia de la lesi\u00f3n endotelial en el pron\u00f3stico del ictus isqu\u00e9mico"},"content":{"rendered":"

Tesis doctoral de Diego Santos Garc\u00eda <\/strong><\/h2>\n

Introducci\u00f3n la vasodilataci\u00f3n dependiente de endotelio (vde) cuantificada mediante doppler en la arteria braquial es una t\u00e9cnica que consiste en cuantificar el grado de dilaci\u00f3n de la luz arterial producido por la liberaci\u00f3n de \u00f3xido n\u00edtrico por el endotelio secundario a un est\u00edmulo mec\u00e1nico generado por el hiperaflujo vascular posterior a la oclusi\u00f3n temporal del vaso. Traduce la bioabilidad de no en el endotelio, y sirve como marcador de disfunci\u00f3n endotelial (de). hip\u00f3tesis la presencia de de durante la fase aguda del ictus condicionar\u00e1 una menor vasodilataci\u00f3n en el \u00e1rea de penumbra isqu\u00e9mica, lo que llevara a una menor recuperaci\u00f3n del tejido cerebral y un peor pron\u00f3stico. objetivos determinar el valor de la vde en el brazo no par\u00e9tico en las primeras 72 horas despu\u00e9s del ictus isqu\u00e9mico y establecer su relaic\u00f3n con el pron\u00f3stico. Adem\u00e1s establecer si existe relaci\u00f3n entre la vde y la presencia de microalbuminuria, engrosamiento intimal y ateromatosis carot\u00eddea. material y m\u00e9todos seleccionamos de forma prospectiva todos los pacientes ingresados con diagn\u00f3stico cl\u00ednico de ictus isqu\u00e9mico hemisf\u00e9rico o s\u00edndrome lacunar de menos de 24 horas de evoluci\u00f3n. Realizamos a todos los pacientes la vde en el brazo no par\u00e9tico en las primeras 72 horas despu\u00e9s del ictus, y consideramos dos grupos: 1,- de cuando la vde es menor o igual a 4,5%. 2,- no de cuando vde es mayor de 4,5% (en relaic\u00f3n con los resultados de la curva roc) resultados la muestra fue de 120 pacientes (58,3% varones, edad media 73 a\u00f1os). Treinta tres pacientes presentaron de (27,5%). La vde fue de 9,12 (7,48). Los de se asoci\u00f3 a engrosamiento intimal (66,7% vs 31,8%, p menor 0,0001), ateromatosis carot\u00eddea (78,8% vsus 47,1%, p = 0,02), y mal pron\u00f3stico (63,6% vsu 20%, p menor 0,0001), as\u00ed como a una mayor puntuaci\u00f3n en la escala nihss basal y en el momento de alta. El modelo de regresi\u00f3n log\u00edstica de mues<\/p>\n

 <\/p>\n

Datos acad\u00e9micos de la tesis doctoral \u00abInfluencia de la lesi\u00f3n endotelial en el pron\u00f3stico del ictus isqu\u00e9mico<\/strong>\u00ab<\/h3>\n
    \n
  • T\u00edtulo de la tesis:<\/strong>\u00a0 Influencia de la lesi\u00f3n endotelial en el pron\u00f3stico del ictus isqu\u00e9mico <\/li>\n
  • Autor:<\/strong>\u00a0 Diego Santos Garc\u00eda <\/li>\n
  • Universidad:<\/strong>\u00a0 Santiago de compostela<\/li>\n
  • Fecha de lectura de la tesis:<\/strong>\u00a0 21\/06\/2007<\/li>\n<\/ul>\n

     <\/p>\n

    Direcci\u00f3n y tribunal<\/h3>\n
      \n
    • Director de la tesis<\/strong>\n
        \n
      • Jos\u00e9 Castillo S\u00e1nchez<\/li>\n<\/ul>\n<\/li>\n
      • Tribunal<\/strong>\n
          \n
        • Presidente del tribunal: manuel Noya Garc\u00eda <\/li>\n
        • joaquin Serena leal (vocal)<\/li>\n
        • Alberto Gil peralta (vocal)<\/li>\n
        • eduardo Mart\u00ednez vila (vocal)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n

           <\/p>\n","protected":false},"excerpt":{"rendered":"

          Tesis doctoral de Diego Santos Garc\u00eda Introducci\u00f3n la vasodilataci\u00f3n dependiente de endotelio (vde) cuantificada mediante doppler en la arteria braquial […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[1880,977],"tags":[19410,130772,18156,37942,21386,2879],"class_list":["post-59187","post","type-post","status-publish","format-standard","hentry","category-neurologia","category-santiago-de-compostela","tag-alberto-gil-peralta","tag-diego-santos-garcia","tag-eduardo-Martinez-vila","tag-joaquin-serena-leal","tag-jose-castillo-sanchez","tag-manuel-noya-garcia"],"_links":{"self":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/59187","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/comments?post=59187"}],"version-history":[{"count":0,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/59187\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/media?parent=59187"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/categories?post=59187"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/tags?post=59187"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}