{"id":61088,"date":"2018-03-09T22:48:55","date_gmt":"2018-03-09T22:48:55","guid":{"rendered":"https:\/\/www.deberes.net\/tesis\/sin-categoria\/convergent-approach-to-the-synthesis-of-myriaporone-4-and-derivatives\/"},"modified":"2018-03-09T22:48:55","modified_gmt":"2018-03-09T22:48:55","slug":"convergent-approach-to-the-synthesis-of-myriaporone-4-and-derivatives","status":"publish","type":"post","link":"https:\/\/www.deberes.net\/tesis\/quimica\/convergent-approach-to-the-synthesis-of-myriaporone-4-and-derivatives\/","title":{"rendered":"Convergent approach to the synthesis of myriaporone 4 and derivatives"},"content":{"rendered":"<h2>Tesis doctoral de <strong> Almudena Diaz Martinez <\/strong><\/h2>\n<p>El objetivo de esta tesis doctoral es la primera s\u00edntesis convergente del metabolito de origen marino, miriaporona 4, que presenta una interesante actividad antitumoral. Para ello se han sintetizado los fragmentos de la mol\u00e9cula para unirlos posteriormente haciendo uso de la reacci\u00f3n ald\u00f3lica con enolatos de boro aprovechando la diastereoselectividad facial de los fragmentos. Otro objetivo de este trabajo es la s\u00edntesis de un derivado ciclopropanado y de un derivado desoxigenado de miriaporona 4 potencialmente activos.<\/p>\n<p>&nbsp;<\/p>\n<h3>Datos acad\u00e9micos de la tesis doctoral \u00ab<strong>Convergent approach to the synthesis of myriaporone 4 and derivatives<\/strong>\u00ab<\/h3>\n<ul>\n<li><strong>T\u00edtulo de la tesis:<\/strong>\u00a0 Convergent approach to the synthesis of myriaporone 4 and derivatives <\/li>\n<li><strong>Autor:<\/strong>\u00a0 Almudena Diaz Martinez <\/li>\n<li><strong>Universidad:<\/strong>\u00a0 Aut\u00f3noma de Madrid<\/li>\n<li><strong>Fecha de lectura de la tesis:<\/strong>\u00a0 26\/10\/2007<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h3>Direcci\u00f3n y tribunal<\/h3>\n<ul>\n<li><strong>Director de la tesis<\/strong>\n<ul>\n<li>Antonio  M. Echavarren Pablos<\/li>\n<\/ul>\n<\/li>\n<li><strong>Tribunal<\/strong>\n<ul>\n<li>Presidente del tribunal: Miguel \u00e1ngel Peric\u00ed\u00a0s brondo <\/li>\n<li>Juan  Alberto Marco ventura (vocal)<\/li>\n<li>julio \u00e1lvarez-builla g\u00f3mez (vocal)<\/li>\n<li>Andr\u00e9s Francesch sollozo (vocal)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tesis doctoral de Almudena Diaz Martinez El objetivo de esta tesis doctoral es la primera s\u00edntesis convergente del metabolito de [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[17,416,32692],"tags":[134948,134949,1384,1886,762,19695],"class_list":["post-61088","post","type-post","status-publish","format-standard","hentry","category-quimica","category-quimica-organica","category-sintesis-y-estructura-de-productos-naturales","tag-almudena-diaz-Martinez","tag-andres-francesch-sollozo","tag-antonio-m-echavarren-pablos","tag-juan-alberto-marco-ventura","tag-julio-alvarez-builla-gomez","tag-miguel-angel-perici-s-brondo"],"_links":{"self":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/61088","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/comments?post=61088"}],"version-history":[{"count":0,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/61088\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/media?parent=61088"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/categories?post=61088"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/tags?post=61088"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}