{"id":63186,"date":"2018-03-09T22:51:06","date_gmt":"2018-03-09T22:51:06","guid":{"rendered":"https:\/\/www.deberes.net\/tesis\/sin-categoria\/the-role-of-the-cell-adhesion-molecule-psa-ncam-in-cortical-development\/"},"modified":"2018-03-09T22:51:06","modified_gmt":"2018-03-09T22:51:06","slug":"the-role-of-the-cell-adhesion-molecule-psa-ncam-in-cortical-development","status":"publish","type":"post","link":"https:\/\/www.deberes.net\/tesis\/histologia-animal\/the-role-of-the-cell-adhesion-molecule-psa-ncam-in-cortical-development\/","title":{"rendered":"The role of the cell adhesion molecule psa ncam in cortical development"},"content":{"rendered":"<h2>Tesis doctoral de <strong> Lilian Enriquez Barreto <\/strong><\/h2>\n<p>Psa is expressed in young neurons of the prenatal cerebral cortex of rodents (seki and arai, 1991) that are regarded today as tangentially migrating interneurons. Previous results have demonstrated the expression of psa-ncam in migrating interneurons of the rostral migratory stream and in fiber systems such as the mossy fibers of the hippocampus (rousselot et al., 1995; rutishauser and landmesser, 1996; cremer et al., 1997; seki and rutishauser, 1998). Important developmental alterations in these two systems have been described in vertebrates due to the absence of psa-ncam. According to these data and taking into consideration some pilot observations from our group, we determined to study the role of ncam on the development of the cerebral cortex using mice deficient for all nca isoforms (cremer et al., 1994).  in this thesis i describe the spatio-temporal patterns of expression of psa and ncam in the telencephalon during the period of embryonic development. I also report alterations found in ncam null animals that are consequences of the lack of this protein. Such observations point to ncam as a molecule that plays certain roles in tangential migration of interneurons and in the proper establishment of thalamocortical projections.<\/p>\n<p>&nbsp;<\/p>\n<h3>Datos acad\u00e9micos de la tesis doctoral \u00ab<strong>The role of the cell adhesion molecule psa ncam in cortical development<\/strong>\u00ab<\/h3>\n<ul>\n<li><strong>T\u00edtulo de la tesis:<\/strong>\u00a0 The role of the cell adhesion molecule psa ncam in cortical development <\/li>\n<li><strong>Autor:<\/strong>\u00a0 Lilian Enriquez Barreto <\/li>\n<li><strong>Universidad:<\/strong>\u00a0 Miguel hern\u00e1ndez de elche<\/li>\n<li><strong>Fecha de lectura de la tesis:<\/strong>\u00a0 28\/02\/2008<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h3>Direcci\u00f3n y tribunal<\/h3>\n<ul>\n<li><strong>Director de la tesis<\/strong>\n<ul>\n<li>Alfonso Fairen Carrion<\/li>\n<\/ul>\n<\/li>\n<li><strong>Tribunal<\/strong>\n<ul>\n<li>Presidente del tribunal: javier De felipe oroquieta <\/li>\n<li>Mar\u00eda  del mar Arroyo jimenez (vocal)<\/li>\n<li>christine Metin (vocal)<\/li>\n<li>Francisco Clasca cabre (vocal)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tesis doctoral de Lilian Enriquez Barreto Psa is expressed in young neurons of the prenatal cerebral cortex of rodents (seki [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[6273,995,2119,730,37169],"tags":[14563,139508,61993,42820,139507,83333],"class_list":["post-63186","post","type-post","status-publish","format-standard","hentry","category-anatomia-animal","category-desarrollo-animal","category-genetica-animal","category-histologia-animal","category-miguel-hernandez-de-elche","tag-alfonso-fairen-carrion","tag-christine-metin","tag-francisco-clasca-cabre","tag-javier-de-felipe-oroquieta","tag-lilian-enriquez-barreto","tag-maria-del-mar-arroyo-jimenez"],"_links":{"self":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/63186","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/comments?post=63186"}],"version-history":[{"count":0,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/63186\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/media?parent=63186"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/categories?post=63186"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/tags?post=63186"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}