{"id":71463,"date":"2018-03-09T23:16:07","date_gmt":"2018-03-09T23:16:07","guid":{"rendered":"https:\/\/www.deberes.net\/tesis\/sin-categoria\/aplicacion-de-modelos-geneticamente-manipulados-knock-out-en-neuro-oftalmologa%c2%ada\/"},"modified":"2018-03-09T23:16:07","modified_gmt":"2018-03-09T23:16:07","slug":"aplicacion-de-modelos-geneticamente-manipulados-knock-out-en-neuro-oftalmologa%c2%ada","status":"publish","type":"post","link":"https:\/\/www.deberes.net\/tesis\/ciencias-medicas\/aplicacion-de-modelos-geneticamente-manipulados-knock-out-en-neuro-oftalmologa%c2%ada\/","title":{"rendered":"Aplicaci\u00f3n de modelos gen\u00e9ticamente manipulados (knock-out) en neuro-oftalmolog\u00eda."},"content":{"rendered":"<h2>Tesis doctoral de <strong>  L\u00f3pez S\u00e1nchez Enrique V. <\/strong><\/h2>\n<p>Nuestro objetivo ha sido estudiar las funciones que realizan las prote\u00ednas apoe, pten y p27kip1, sobre el nervio \u00f3ptico (no) y retina.  este trabajo se ha llevado a cabo en ratones distribuidos en cinco grupos: 1) ratones wildtype (grupo control), 2) ratones apoe knockout (grupo apoe), 3) ratones apoe knockout suplementados con una dieta hipercolesterol\u00e9mica (apoe+d), 4) ratones heterocigotos pten knockout, (grupo pten) y 5) ratones p27kip1  knockout (grupo p27).  en los grupos apoe y apoe+d, tanto las \u00e1reas de la secci\u00f3n trasversal del no como de los axones fueron significativamente mayores que las  del grupo<\/p>\n<p>&nbsp;<\/p>\n<h3>Datos acad\u00e9micos de la tesis doctoral \u00ab<strong>Aplicaci\u00f3n de modelos gen\u00e9ticamente manipulados (knock-out) en neuro-oftalmolog\u00eda.<\/strong>\u00ab<\/h3>\n<ul>\n<li><strong>T\u00edtulo de la tesis:<\/strong>\u00a0 Aplicaci\u00f3n de modelos gen\u00e9ticamente manipulados (knock-out) en neuro-oftalmolog\u00eda. <\/li>\n<li><strong>Autor:<\/strong>\u00a0  L\u00f3pez S\u00e1nchez Enrique V. <\/li>\n<li><strong>Universidad:<\/strong>\u00a0 Universitat de val\u00e9ncia (estudi general)<\/li>\n<li><strong>Fecha de lectura de la tesis:<\/strong>\u00a0 26\/11\/2004<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h3>Direcci\u00f3n y tribunal<\/h3>\n<ul>\n<li><strong>Director de la tesis<\/strong>\n<ul>\n<li>Jos\u00e9 Luis Menezo Rozalen<\/li>\n<\/ul>\n<\/li>\n<li><strong>Tribunal<\/strong>\n<ul>\n<li>Presidente del tribunal: manuel Vidal sanz <\/li>\n<li>Elena Vecino cordero (vocal)<\/li>\n<li> Villegas perez M\u00aa paz (vocal)<\/li>\n<li>Jos\u00e9 ignacio Gonz\u00e1lez arraez (vocal)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tesis doctoral de L\u00f3pez S\u00e1nchez Enrique V. Nuestro objetivo ha sido estudiar las funciones que realizan las prote\u00ednas apoe, pten [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[155,9,141,2606,1686,988],"tags":[42800,154344,26986,155715,7462,155716],"class_list":["post-71463","post","type-post","status-publish","format-standard","hentry","category-ciencias-clinicas","category-ciencias-medicas","category-cirugia","category-cirugia-ocular","category-medicina-preventiva","category-oftalmologia","tag-elena-vecino-cordero","tag-jose-ignacio-gonzalez-arraez","tag-jose-luis-menezo-rozalen","tag-lopez-sanchez-enrique-v","tag-manuel-vidal-sanz","tag-villegas-perez-ma-paz"],"_links":{"self":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/71463","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/comments?post=71463"}],"version-history":[{"count":0,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/71463\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/media?parent=71463"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/categories?post=71463"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/tags?post=71463"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}