{"id":86734,"date":"2000-02-10T00:00:00","date_gmt":"2000-02-10T00:00:00","guid":{"rendered":"https:\/\/www.deberes.net\/tesis\/sin-categoria\/studies-on-synthesis-of-new-chiral-multiply-substituted-fluorene-diervatives-and-first-attempts-to-study-their-use-as-low-molecule-and-side-chain-polymer-liquid-crystal\/"},"modified":"2000-02-10T00:00:00","modified_gmt":"2000-02-10T00:00:00","slug":"studies-on-synthesis-of-new-chiral-multiply-substituted-fluorene-diervatives-and-first-attempts-to-study-their-use-as-low-molecule-and-side-chain-polymer-liquid-crystal","status":"publish","type":"post","link":"https:\/\/www.deberes.net\/tesis\/quimica\/studies-on-synthesis-of-new-chiral-multiply-substituted-fluorene-diervatives-and-first-attempts-to-study-their-use-as-low-molecule-and-side-chain-polymer-liquid-crystal\/","title":{"rendered":"Studies on synthesis of new chiral multiply substituted fluorene diervatives and first attempts to study their use as low-molecule and side-chain polymer liquid crystal"},"content":{"rendered":"<h2>Tesis doctoral de <strong> Zhanru Yu <\/strong><\/h2>\n<p>En el presente trabajo se plantea la obtenci\u00f3n de fluorenos polifuncionalizados quirales. El objetivo es el desarrollo de un camino sint\u00e9tico que conduzca a fluorenonas polisubstitu\u00eddas como precursores de derivados de fluorenos quirales, que por posterior transformaci\u00f3n de los grupos funcionales introducidos en el sistema arom\u00e1tico permitan la obtenci\u00f3n de mol\u00e9culas pre-mesog\u00e9nicas convenientemente funcionalizadas para su introducci\u00f3n posterior en la cadena de poli (hidr\u00f3genometilsiloxano) dando lugar a pol\u00edmeros de cadena lateral.  a partir de los trabajos realizados en la presente tesis doctoral, se pueden extraer las siguientes conclusiones:  1,- se ha establecido un m\u00e9todo para determinar la resoluci\u00f3n \u00f3ptica de distintos 9-fluorenilderivados a partir de su an\u00e1lisis por cromatograf\u00eda quiral de hplc sobre un alil-s\u00edlice no comercial.  2,- se ha obtenido un 84% de exceso enantiom\u00e9rico en (s)-1-bromofluoren-9-ol por reducci\u00f3n de la correspondiente 1-bromofluoren-9-ona con borano en presencia del amino alcohol (s)-alfa, alfa-difenil-2-pirrolidinmetanol.  3,- se han obtenido rendimiento qu\u00edmicos aceptables (61-98%) para los procesos de reducci\u00f3n de diferentes fluorenon-9-onas 1-substitu\u00eddas con hidruro de aluminio y litio en presencia de amino alcoholes quirales.  4,- se ha descrito un proceso sint\u00e9tico en dos pasos para la obtenci\u00f3n de fluoren-9-onas polifuncionalizadas mediante una cilcaci\u00f3n intramolecular de sistemas 3-aminobifenil-2,4-dicarbonitrilos diferentes substitu\u00eddos.  5,- se ha desarrollado una ruta sint\u00e9tica para la preparaci\u00f3n de diversos mon\u00f3meros conteniendo como n\u00facleo central el fluorenol o la fluorenona.  6,- se ha obtendio el (-)-9-acetoxi-1-bromo-7-(4-(undec-10-eniloxi)benzoilamino)-9h-fluoren-3-carboxilato de undecilo, principal objetivo sint\u00e9tico del presente trabajo con un elevado exceso enantiom\u00e9rico (91%) mediante los procesos optimizados de reducci\u00f3n asim\u00e9trica mencionados<\/p>\n<p>&nbsp;<\/p>\n<h3>Datos acad\u00e9micos de la tesis doctoral \u00ab<strong>Studies on synthesis of new chiral multiply substituted fluorene diervatives and first attempts to study their use as low-molecule and side-chain polymer liquid crystal<\/strong>\u00ab<\/h3>\n<ul>\n<li><strong>T\u00edtulo de la tesis:<\/strong>\u00a0 Studies on synthesis of new chiral multiply substituted fluorene diervatives and first attempts to study their use as low-molecule and side-chain polymer liquid crystal <\/li>\n<li><strong>Autor:<\/strong>\u00a0 Zhanru Yu <\/li>\n<li><strong>Universidad:<\/strong>\u00a0 Barcelona<\/li>\n<li><strong>Fecha de lectura de la tesis:<\/strong>\u00a0 02\/10\/2000<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h3>Direcci\u00f3n y tribunal<\/h3>\n<ul>\n<li><strong>Director de la tesis<\/strong>\n<ul>\n<li>Dolores Velasco Castrillo<\/li>\n<\/ul>\n<\/li>\n<li><strong>Tribunal<\/strong>\n<ul>\n<li>Presidente del tribunal: fernando Albericio palomera <\/li>\n<li>joan carles Ronda bargall\u00f3 (vocal)<\/li>\n<li>cristina Minquillon llombart (vocal)<\/li>\n<li>josep Mar\u00eda Moret\u00f3 canela (vocal)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tesis doctoral de Zhanru Yu En el presente trabajo se plantea la obtenci\u00f3n de fluorenos polifuncionalizados quirales. El objetivo es [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[951,1412,17,6308,966],"tags":[181914,42356,1099,117865,1385,181913],"class_list":["post-86734","post","type-post","status-publish","format-standard","hentry","category-barcelona","category-compuestos-heterociclicos","category-quimica","category-quimica-de-monomeros","category-quimica-macromolecular","tag-cristina-minquillon-llombart","tag-dolores-velasco-castrillo","tag-fernando-albericio-palomera","tag-joan-carles-ronda-bargallo","tag-josep-maria-moreto-canela","tag-zhanru-yu"],"_links":{"self":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/86734","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/comments?post=86734"}],"version-history":[{"count":0,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/posts\/86734\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/media?parent=86734"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/categories?post=86734"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.deberes.net\/tesis\/wp-json\/wp\/v2\/tags?post=86734"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}