{"id":97330,"date":"2018-03-11T10:17:50","date_gmt":"2018-03-11T10:17:50","guid":{"rendered":"https:\/\/www.deberes.net\/tesis\/sin-categoria\/antitumorigenic-mechanisms-of-action-of-peroxisome-proliferator-activated-gamma-ppargamma-ligands-in-breast-cancer\/"},"modified":"2018-03-11T10:17:50","modified_gmt":"2018-03-11T10:17:50","slug":"antitumorigenic-mechanisms-of-action-of-peroxisome-proliferator-activated-gamma-ppargamma-ligands-in-breast-cancer","status":"publish","type":"post","link":"https:\/\/www.deberes.net\/tesis\/sin-categoria\/antitumorigenic-mechanisms-of-action-of-peroxisome-proliferator-activated-gamma-ppargamma-ligands-in-breast-cancer\/","title":{"rendered":"Antitumorigenic mechanisms of action of peroxisome proliferator-activated gamma (ppargamma) ligands in breast cancer"},"content":{"rendered":"<h2>Tesis doctoral de <strong> Jorge Dorado Perez <\/strong><\/h2>\n<p>In this work we have analyzed the antitumorigenic mechanisms of action of the peroxisome proliferator-activated receptor gamma (ppargamma) ligands 15-deoxi-12,14-prostaglandin j2 , rosiglitazone and pioglitazone on human breast cancer cells. Our data show that treatment with these compounds reduces cell viability, induces inhibition of proliferation and promotes apoptosis in several breast carcinoma cell lines, and attribute for the first time similar effects to members of the thiadiazolidinones (tdzds) family of compounds.<\/p>\n<p>&nbsp;<\/p>\n<h3>Datos acad\u00e9micos de la tesis doctoral \u00ab<strong>Antitumorigenic mechanisms of action of peroxisome proliferator-activated gamma (ppargamma) ligands in breast cancer<\/strong>\u00ab<\/h3>\n<ul>\n<li><strong>T\u00edtulo de la tesis:<\/strong>\u00a0 Antitumorigenic mechanisms of action of peroxisome proliferator-activated gamma (ppargamma) ligands in breast cancer <\/li>\n<li><strong>Autor:<\/strong>\u00a0 Jorge Dorado Perez <\/li>\n<li><strong>Universidad:<\/strong>\u00a0 Aut\u00f3noma de Madrid<\/li>\n<li><strong>Fecha de lectura de la tesis:<\/strong>\u00a0 20\/11\/2009<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h3>Direcci\u00f3n y tribunal<\/h3>\n<ul>\n<li><strong>Director de la tesis<\/strong>\n<ul>\n<li>Ana Mar\u00eda P\u00e9rez Castillo<\/li>\n<\/ul>\n<\/li>\n<li><strong>Tribunal<\/strong>\n<ul>\n<li>Presidente del tribunal: pilar Santisteban sanz <\/li>\n<li>Jorge Martin perez (vocal)<\/li>\n<li>gregorio angel Santos montes (vocal)<\/li>\n<li>rosario Perona abellon (vocal)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tesis doctoral de Jorge Dorado Perez In this work we have analyzed the antitumorigenic mechanisms of action of the peroxisome [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center 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